5447-61-0Relevant academic research and scientific papers
A general N-alkylation procedure for ethyl pyroglutamate
Simandan, Tiberiu,Smith, Michael B.
, p. 1827 - 1838 (2007/10/03)
Despite several reported procedures for coupling alkyl halides and 5-oxoproline esters (pyroglutamate derivatives), no general method has been described. The reaction of pyrroglutamate with sodium hydride, in anhydrous THF in the presence of the halide, p
Studies on pyrrolidinones. Michael reaction of glutamic acid and diethylglutamate
Rigo, Benoit,Couturier, Daniel,Kolocouris, Nicolas
, p. 1769 - 1772 (2007/10/02)
Starting from glutamic acid or diethyl glutamate, some derivatives of N-(2-carboxyethyl), N-(3-oxobutyl) and N-(2-cyanoethyl)pyroglutamic acid were synthesized.
