544706-65-2Relevant academic research and scientific papers
Synthesis of buta-1,3-diyne-bridged macrocycles with (Z)-1,4-diethynyl-1,4-dimethoxycyclohexa-2,5-diene as the building block
Srinivasan, Manivannan,Sankararaman, Sethuraman,Hopf, Henning,Varghese, Babu
, p. 660 - 665 (2003)
(Z)-1,4-Diethynyl-1,4-dimethoxycyclohexa-2,5-diene has been used as a building block for the synthesis of two novel macrocycles containing buta-1,3-diyne units as bridges. The tetrayne derivative 5c has been structurally characterized by single crystal X-ray crystallographic data. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
Synthesis of strained pyridine-containing cyclyne via reductive aromatization
Miki, Koji,Fujita, Michiyasu,Inoue, Yuki,Senda, Yoshinori,Kowada, Toshiyuki,Ohe, Kouichi
supporting information; scheme or table, p. 3537 - 3540 (2010/08/03)
The Sonogashira-Hagihara coupling reactions of 2,6-diiodopyridine and cis-3,6-diethynyl-3,6-dimethoxycyclohexa-1,4-diene or cis-9,10-diethynyl-9,10- dimethoxy-9,10-dihydroanthracene gave macrocyclic compounds having alternating 2,6-diethynylpyridine and 3,6-dimethoxycyclohexa-1,4-diene segments. Transformation of the C3-symmetric 2,6-diethynylpyridine-based cyclotrimer was efficiently achieved using tin-mediated reductive aromatization under mild conditions.
