544709-66-2 Usage
Methyl ester derivative
2-(4-bromo-2-nitrophenyl)-2-methylpropionic acid The compound is derived from 2-(4-bromo-2-nitrophenyl)-2-methylpropionic acid by replacing the carboxylic acid group (-COOH) with a methyl ester group (-COOCH3).
Usage in organic synthesis
Commonly used 2-(4-bromo-2-nitro-phenyl)-2-methyl-propionic acid methyl ester is frequently utilized in organic synthesis due to its reactive functional groups, which allow for various chemical reactions and the formation of new compounds.
Pharmaceutical research
Application in drug development The compound may be used as an intermediate in the production of various drugs and pharmaceuticals, making it valuable in the field of pharmaceutical research.
Hazardous properties
Proper management required 2-(4-bromo-2-nitro-phenyl)-2-methyl-propionic acid methyl ester can be hazardous if not handled correctly, so it is essential to follow appropriate safety precautions when working with it.
Safety precautions
Necessary when working with the compound To ensure the safety of individuals and the environment, it is crucial to take proper safety measures when handling, storing, and disposing of this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 544709-66-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,4,7,0 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 544709-66:
(8*5)+(7*4)+(6*4)+(5*7)+(4*0)+(3*9)+(2*6)+(1*6)=172
172 % 10 = 2
So 544709-66-2 is a valid CAS Registry Number.
544709-66-2Relevant academic research and scientific papers
8 - SUBSTITUTED 2 -AMINO - [1,2,4] TRIAZOLO [1, 5 -A] PYRAZINES AS SYK TRYROSINE KINASE INHIBITORS AND GCN2 SERIN KINASE INHIBITORS
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Page/Page column 125, (2013/09/12)
Compounds of the formula I in which R1, R2 and R4 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of cancer, rheumatoid arthritis and / or systemic lupus
TRIAZOLOPYRAZINE DERIVATIVES
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Page/Page column 81; 82, (2013/09/26)
Compounds of the formula (I) in which R1, R2 and R4 have the meanings indicated in Claim 1, are inhibitors of GCN2, and can be employed, inter alia, for the treatment of cancer.
Iron(II) bromide-catalyzed intramolecular c-h bond amination [1,2]-shift tandem reactions of aryl azides
Nguyen, Quyen,Nguyen, Tuyen,Driver, Tom G.
supporting information, p. 620 - 623 (2013/03/13)
Iron(II) bromide catalyzes the transformation of ortho-substituted aryl azides into 2,3-disubstituted indoles through a tandem ethereal C-H bond amination [1,2]-shift reaction. The preference for the 1,2-shift component of the tandem reaction was established to be Me 1 2 Ph.
CHEMICAL ENCODING TECHNOLOGY FOR COMBINATORIAL SYNTHESIS
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Page 22, (2008/06/13)
A chemical tag can include a core and a plurality of substituents attached directly to the core. The substituents of each chemical tag form a subset of a closed set of possible substituents. The tag can be used to track an object.
