54482-57-4

Upstream product

• 4575-74-0 cycloartanyl acetate 
• 943985-75-9 C₃₆H₅₆O₂Se 
• 4936-10-1 9,19-cyclolanostan-3-one 
• 4657-58-3 cycloartanol 
• 469-38-5 cycloartenol 
• 26955-76-0 cycloartan-24,25-epoxy-3β-ol 

Relevant academic research and scientific papers

Structural revision of terpenoids with a (3Z)-2-methyl-3-penten-2-ol moiety by the synthesis of (23E)- and (23Z)-cycloart-23-ene-3β,25-diols

(Chemical Equation Presented) Synthesis of (23E)-cycloart-23-ene-3β, 25-diol (1) and its 23Z-isomer 2 was achieved by using cycloartenol as a starting material, thus revising the proposed structure of natural 2 to 1 unequivocally. These synthetic studies

Cytotoxic triterpenoids from the leaves of Euphorbia pulcherrima

Two cytotoxic triterpenes have been isolated from Euphorbia pulcherrima. Their structures and stereochemistry have been established from NMR, IR, and EI-mass spectroscopy. The compounds were identified as 9,19-cycloart-23-ene-3β,25-diol and 9,19-cycloart-25-ene-3β,24-diol. Cytotoxicity evaluation was performed using Ehrlich ascites tumor cells. While cycloartenol induced no cytotoxic activity against Ehrlich ascites tumor cells, both isolated triterpenes exhibited cell inactivating effects. The IC50 is approximately 7.5 μM, while the IC90 is approximately 13.5 μM for 9,19-cycloart-25-ene-3β,24-diol. The 3β,25-diol compound is 50% less active.