545-27-7 Usage
Uses
Used in Pharmaceutical Industry:
(3α,5α,16α)is used as a potential therapeutic agent for its anti-inflammatory, anticancer, and antioxidant properties. Its unique structure may provide novel biological activities that can be further explored for the development of new drugs.
Used in Cosmetic Industry:
(3α,5α,16α)can be used as an active ingredient in cosmetic products for its potential anti-inflammatory and antioxidant effects, which may help in reducing skin inflammation and promoting skin health.
Used in Nutraceutical Industry:
(3α,5α,16α)can be incorporated into dietary supplements or functional foods for its potential health benefits, such as reducing inflammation and promoting overall well-being.
Used in Agricultural Industry:
(3α,5α,16α)can be used as a natural pesticide or growth promoter in agriculture, due to its potential anti-inflammatory and antioxidant properties, which may help in improving crop health and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 545-27-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 545-27:
(5*5)+(4*4)+(3*5)+(2*2)+(1*7)=67
67 % 10 = 7
So 545-27-7 is a valid CAS Registry Number.
545-27-7Relevant academic research and scientific papers
Cardiac Glycosides. 6. Gitoxigenin C16 Acetates, Formates, Methoxycarbonates, and Digitoxosides. Synthesis and Na+, K+ -ATPase Inhibitory Activities
Hashimoto, Toshihiro,Rathore, Hargovind,Satoh, Daisuke,Hong, George,Griffin, Jane F.,et al.
, p. 997 - 1003 (2007/10/02)
A series of 17 gitoxigenin 16β-formates, acetates, and methoxycarbonates was synthesized, including their 3β-acetates, formates, and digitoxosides.A 16β-formate group was generally found to increase activity 30 times, a 16β-acetate group 9-12 times, while a 16β-methoxycarbonate decreased activity by two-thirds. 3β-Formates and acetates had little effect on activity by themselves, but sometimes reduced the activity-increasing properties of 16β-formates and acetates.A 3β-digitoxoside increases the activity of ditoxigenin by 15 times, but the effect is less ifthe 16β-group is esterified.And finally, a 16-one decreases activity dramatically.These data suggest an important role for C16 esters and possibly the presence of a separate binding site on Na+, K+ -ATPase corresponding to the cardenolide C16 position.
