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545-51-7

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  • 5-[(10R,13R,14S,17R)-14-hydroxy-10,13-dimethyl-1,2,7,8,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one

    Cas No: 545-51-7

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545-51-7 Usage

Chemical structure

14β-Hydroxybufa-3,5,20,22-tetrenolide is a cardiac glycoside compound with a specific chemical structure that includes a steroidal backbone and a lactone ring.

Source

It is found in various plants, such as squill and toad venom.

Toxicity

It is a highly toxic compound and must be used with extreme caution and under the supervision of a qualified healthcare professional.

Cardiotonic effects

It increases the contractile force of the heart by inhibiting the sodium-potassium pump.

Cytotoxic effects

It stimulates apoptosis in cancer cells, making it potentially useful in treating certain types of cancer.

Anti-inflammatory and anti-fibrotic effects

It has shown potential as an anti-inflammatory and anti-fibrotic agent.

Therapeutic index

It has a narrow therapeutic index, which means that the difference between the effective dose and the toxic dose is small.

Side effects

Its use is limited due to its potential for severe side effects, which can include heart problems and other serious complications.

Medical supervision

It must be used under the supervision of a qualified healthcare professional to ensure safe and effective treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 545-51-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 545-51:
(5*5)+(4*4)+(3*5)+(2*5)+(1*1)=67
67 % 10 = 7
So 545-51-7 is a valid CAS Registry Number.
InChI:InChI=1/C24H30O3/c1-22-12-4-3-5-17(22)7-8-20-19(22)10-13-23(2)18(11-14-24(20,23)26)16-6-9-21(25)27-15-16/h3,5-7,9,15,18-20,26H,4,8,10-14H2,1-2H3/t18-,19?,20?,22+,23-,24+/m1/s1

545-51-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-[(10R,13R,14S,17R)-14-hydroxy-10,13-dimethyl-1,2,7,8,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one

1.2 Other means of identification

Product number -
Other names 14-Hydroxy-bufa-3,5,20,22-tetraenolide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:545-51-7 SDS

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