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12α-Hydroxysterone is a naturally occurring steroid hormone that is a metabolite of the hormone cortisol. It is formed in the body through the action of the enzyme 11β-hydroxysteroid dehydrogenase type 1, which converts cortisol to cortisone. This conversion is part of the body's feedback mechanism to regulate cortisol levels. 12α-Hydroxysterone has been studied for its potential role in various physiological processes and diseases, including the regulation of blood pressure and glucose metabolism. It is also of interest in the field of endocrinology due to its involvement in the stress response and its potential impact on health conditions such as Cushing's syndrome. The compound is not typically used as a medication but is an important biomarker in medical research and diagnostics.

545-76-6

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545-76-6 Usage

Natural chemical compound

Found in the roots of plants from the genus Caesalpinia.

Family

Member of the rotenoid family.

Insecticidal and pesticidal properties

Known for their insecticidal and pesticidal properties.

Potential use

Studied for its potential use as a biopesticide.

Pest activity

Shown activity against a variety of pests, including mosquitoes, ticks, and agricultural pests.

Cytotoxic and antitumor properties

Exhibits cytotoxic and antitumor properties.

Pharmaceutical applications

Subject of interest for potential pharmaceutical applications.

Antioxidant effects

Investigated for its antioxidant effects.

Antidiabetic effects

Investigated for its antidiabetic effects.

Further research needed

Important to note that further research is needed to fully understand the potential benefits and risks associated with this chemical.

Check Digit Verification of cas no

The CAS Registry Mumber 545-76-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 545-76:
(5*5)+(4*4)+(3*5)+(2*7)+(1*6)=76
76 % 10 = 6
So 545-76-6 is a valid CAS Registry Number.
InChI:InChI=1/C23H22O7/c1-11(2)16-7-13-15(29-16)6-5-12-21(13)30-20-10-28-17-9-19(27-4)18(26-3)8-14(17)23(20,25)22(12)24/h5-6,8-9,16,20,25H,1,7,10H2,2-4H3/t16-,20-,23+/m1/s1

545-76-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Rotenolone

1.2 Other means of identification

Product number -
Other names 12-Azabenzo[a]pyren

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:545-76-6 SDS

545-76-6Upstream product

545-76-6Downstream Products

545-76-6Relevant academic research and scientific papers

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