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Vincristine, also known as Voacristine, is a naturally occurring vinca alkaloid derived from the Madagascar periwinkle plant (Catharanthus roseus). It is a potent chemotherapeutic agent that works by inhibiting the formation of microtubules, which are essential for cell division. This action leads to the disruption of the cell cycle, ultimately resulting in cell death. Vincristine is primarily used to treat various types of cancer, including leukemia, lymphoma, and some solid tumors. It is often administered in combination with other chemotherapeutic drugs to enhance its effectiveness. Due to its narrow therapeutic index, vincristine requires careful monitoring and dose adjustments to minimize side effects, which can include neurotoxicity, constipation, and bone marrow suppression.

545-84-6

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545-84-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 545-84-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 5 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 545-84:
(5*5)+(4*4)+(3*5)+(2*8)+(1*4)=76
76 % 10 = 6
So 545-84-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H28N2O4/c1-12(25)16-8-13-10-22(21(26)28-3)19-15(6-7-24(11-13)20(16)22)17-9-14(27-2)4-5-18(17)23-19/h4-5,9,12-13,16,20,23,25H,6-8,10-11H2,1-3H3/t12-,13+,16+,20-,22+/m0/s1

545-84-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name VOACANGARINE

1.2 Other means of identification

Product number -
Other names COACRISTINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:545-84-6 SDS

545-84-6Upstream product

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