54503-77-4Relevant academic research and scientific papers
Inhibition of human cytomegalovirus protease N(o) with monocyclic β- lactams
Deziel,Malenfant
, p. 1437 - 1442 (2007/10/03)
Monocyclic β-lactams have been identified as potent and selective inhibitors of the human cytomegalovirus protease (HCMV) N(o). Two series of these inhibitors are described, a peptidyl series of compounds and non- peptidic molecules featuring lower molecular weights. The SAR work that lead to the discovery of these inhibitors, together with their synthesis is also disclosed.
