5451-50-3

Usage

Uses

Used in Fragrance Industry:
2-methoxyethyl 4-methoxybenzoate is used as a fragrance ingredient for its sweet, floral scent, enhancing the olfactory experience in perfumes, lotions, and other personal care products.
Used in Food Industry:
In the food industry, 2-methoxyethyl 4-methoxybenzoate is utilized as a flavoring agent, imparting a pleasant taste to various food products and contributing to their overall sensory appeal.
Used in Pharmaceutical Industry:
2-methoxyethyl 4-methoxybenzoate is employed in some antifungal medications due to its antifungal properties, making it a valuable component in the treatment and prevention of fungal infections.

Upstream product

• 109-86-4 2-methoxy-ethanol 
• 201230-82-2 carbon monoxide 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 3400-22-4 4-methoxy-N-methylbenzamide 
• 104-93-8 p-methylanizole 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant academic research and scientific papers

Electro-Oxidative Selective Esterification of Methylarenes and Benzaldehydes

A mild and green electro-oxidative protocol to construct aromatic esters from methylarenes and alcohols is herein reported. Importantly, the reaction is free of metals, chemical oxidants, bases, acids, and operates at room temperature. Moreover, the design of the electrolyte was found critical for the oxidation state and structure of the coupling products, a rarely documented effect. This electro-oxidative coupling process also displays exceptional tolerance of many fragile easily oxidized functional groups such as hydroxy, aldehyde, olefin, alkyne, as well as neighboring benzylic positions. The enantiomeric enrichment of some chiral alcohols is moreover preserved during this electro-oxidative coupling reaction, making it overall a promising synthetic tool.

Cobalt-Catalyzed Esterification of Amides

The first cobalt-catalyzed amide activation of N-Boc-amides, and their conversion into esters, is reported here. This new methodology presents a very practical process that does not require an inert atmosphere, uses an inexpensive cobalt catalyst, and proceeds under mild reaction conditions. This catalytic system has a broad substrate scope and has been shown to be highly efficient, with catalyst loadings as low as 1 mol %.

Metal-free, room-temperature, radical alkoxycarbonylation of aryldiazonium salts through visible-light photoredox catalysis

The first radical alkoxycarboxylation of aryldiazonium salts using CO gas through visible-light-induced photoredox catalysis (16 W blue LEDs) has been developed. This reaction is entirely metal-free, is carried out at room temperature with a low loading of an organic dye as a photocatalyst (0.5 mol%), and provides a wide range of arylcarboxylic acid esters in high yields. Importantly, this photocatalytic system can be successfully extended to other carboxylation reactions.