54518-97-7Relevant academic research and scientific papers
PROCESS FOR PREPARING AMINES FROM ALCOHOLS AND AMMONIA
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Page/Page column 24; 31; 32, (2010/04/03)
The present invention provides novel ruthenium based catalysts, and a process for preparing amines, by reacting a primary alcohol and ammonia in the presence of such catalysts, to generate the amine and water. According to the process of the invention, primary alcohols react directly with ammonia to produce primary amines and water in high yields and high turnover numbers. This reaction is catalyzed by novel ruthenium complexes, which are preferably composed of quinolinyl or acridinyl based pincer ligands.
Selective synthesis of primary amines directly from alcohols and ammonia
Gunanathan, Chidambaram,Milstein, David
supporting information; experimental part, p. 8661 - 8664 (2009/05/15)
(Chemical Equation Presented) Air stable and waterproof: Selective and efficient synthesis of primary amines directly from alcohols and ammonia is achieved under mild conditions (see scheme). The reaction is homogenously catalyzed by a novel air-stable ruthenium pincer complex and can proceed in toluene or even in the absence of solvent or "on water".
