54526-95-3Relevant academic research and scientific papers
Hemisynthesis, Antitumoral Effect, and Molecular Docking Studies of Ferutinin and Its Analogues
Safi, Rmi,Rodriguez, Frderic,Hilal, Georges,Diab-Assaf, Mona,Diab, Youssef,El-Sabban, Marwan,Najjar, Fadia,Delfourne, Evelyne
, p. 382 - 397 (2016/03/12)
The natural product ferutinin was shown to act as an agonist to estrogen receptor ERα and agonist/antagonist to ERβ featuring a weak antiproliferative activity toward breast cancer cells. To enhance this activity, ferutinin analogues were synthesized by e
Daucane phytoestrogens: A structure-activity study
Appendino, Giovanni,Spagliardi, Paola,Cravotto, Giancarlo,Pocock, Victoria,Milligan, Stuart
, p. 1612 - 1615 (2007/10/03)
The estrogenic activity of a series of analogues of the daucane ester ferutinin (1a) modified at the acyl moiety was investigated in a yeast screen containing the human estrogen receptor α. Rather strict structure - activity relationships were observed. T
