54533-29-8

Usage

Uses

Used in Pharmaceutical Applications:
1-(2-methyl-1-oxobut-2-enyl)piperidine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable building block in the development of new drugs with potential therapeutic applications.
Used in Industrial Applications:
In the industrial sector, 1-(2-methyl-1-oxobut-2-enyl)piperidine may be utilized as a component in the production of specialty chemicals, materials, or coatings. Its specific chemical properties could be harnessed to create novel products with unique characteristics, such as improved performance or enhanced functionality.

InChI:InChI=1/C10H17NO/c1-3-9(2)10(12)11-7-5-4-6-8-11/h3H,4-8H2,1-2H3

Upstream product

• 110-89-4 piperidine 
• 201230-82-2 carbon monoxide 
• 103185-13-3 (E)-crotyl methyl carbonate 

Relevant academic research and scientific papers

Ruthenium Complex-Catalyzed Carbonylation of Allylic Compounds

Allylic alkyl carbonates are carbonylated under 40 atm of carbon monoxide at 100-120 deg C in the presence of a catalytic amount of Ru3(CO)12/1,10-phenanthroline to give α,β- or β,γ-unsaturated esters in good to high yields.For example, cinnamyl methyl carbonate afforded the corresponding β,γ-unsaturated esters, methyl trans-4-phenyl-3-butenoate (1) in 93percent yield.The regioselectivity in the carbonylation of crotyl methyl carbonate is unusual and it depends on the carbon monoxide pressure.The more sterically hindered carbon (γ-carbon) is predominantly carbonylated at 20-50 atm.When the reaction of cinnamyl methyl carbonate was performed at elevated temperature (150 deg C) without 1,10-phenanthroline, the dimer of 1, dimethyl 3-benzyl-2-(trans-2-phenylvinyl)glutarate, was obtained in 56percent yield.In the presence of secondary amines, allylic alkyl carbonates were carbonylated mainly at α-carbon to give α,β- or β,γ-unsaturated amides in high yields.