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Nizofenone is a chemical compound belonging to the class of organonitrogen compounds, specifically nitrosamides. It is a potent and selective inhibitor of the enzyme acyl-coenzyme A: cholesterol acyltransferase (ACAT), which plays a crucial role in cholesterol metabolism by catalyzing the esterification of cholesterol in the body. Nizofenone has been studied for its potential therapeutic applications in the treatment of hypercholesterolemia, atherosclerosis, and cardiovascular diseases. Its mechanism of action involves reducing the accumulation of cholesterol in the body, thereby lowering the risk of plaque formation and improving overall cardiovascular health.

54533-86-7

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54533-86-7 Usage

Uses

Used in Pharmaceutical Industry:
Nizofenone is used as a therapeutic agent for the treatment of hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood. It helps in reducing the accumulation of cholesterol in the body, thereby lowering the risk of plaque formation and improving overall cardiovascular health.
Used in Cardiovascular Disease Management:
Nizofenone is used as a potential therapeutic agent in the management of cardiovascular diseases, including atherosclerosis. Its mechanism of action involves inhibiting the enzyme ACAT, which plays a critical role in cholesterol metabolism. By reducing the accumulation of cholesterol, nizofenone can help lower the risk of plaque formation and improve overall cardiovascular health.
Used in Atherosclerosis Treatment:
Nizofenone is used as a potential therapeutic agent in the treatment of atherosclerosis, a condition characterized by the buildup of plaque in the arteries. Its ability to inhibit the enzyme ACAT and reduce cholesterol accumulation can help in lowering the risk of plaque formation and improving overall cardiovascular health.
Further research is ongoing to explore the full potential and applicability of nizofenone in clinical settings, as it holds promise in the development of novel therapeutic strategies for the treatment of hypercholesterolemia, atherosclerosis, and cardiovascular diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 54533-86-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,5,3 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 54533-86:
(7*5)+(6*4)+(5*5)+(4*3)+(3*3)+(2*8)+(1*6)=127
127 % 10 = 7
So 54533-86-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H21ClN4O3.C4H4O4/c1-3-24(4-2)14-20-23-11-12-25(20)19-10-9-15(26(28)29)13-17(19)21(27)16-7-5-6-8-18(16)22;5-3(6)1-2-4(7)8/h5-13H,3-4,14H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

54533-86-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (2-Chlorophenyl)(2-{2-[(diethylamino)methyl]-1H-imidazol-1-yl}-5- nitrophenyl)methanone

1.2 Other means of identification

Product number -
Other names Ethanehydrazonothioic acid,2-nitro-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54533-86-7 SDS

54533-86-7Upstream product

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