545362-95-6

Upstream product

• 55149-84-3 2-nitroveratraldehyde 

Downstream Products

• 545363-32-4 (11S)-(12Z)-11-ethoxycarbonylmethyl-11-formyl-1,2-dimethoxy-7-(2-nitro-benzenesulfonyl)-6,7,8,9,10,11-hexahydro-5H-7,14-diaza-cycloundeca[a]indene-14-carboxylic acid tert-butyl ester 
• 545363-06-2 (11S)-(12Z)-11-dimethoxymethyl-11-ethoxycarbonylmethyl-1,2-dimethoxy-7-(2-nitro-benzenesulfonyl)-6,7,8,9,10,11-hexahydro-5H-7,14-diaza-cycloundeca[a]indene-14-carboxylic acid tert-butyl ester 
• 545363-04-0 (1'Z)-(3'S)-2-(3'-dimethoxymethyl-3'-ethoxycarbonylmethyl-6'-hydroxy-hex-1'-enyl)-6,7-dimethoxy-3-[2-(2-nitro-benzenesulfonylamino)-ethyl]-indole-1-carboxylic acid tert-butyl ester 
• 545363-28-8 (1'Z)-(3'S)-2-[6'-(tert-butyldiphenyl-silanyloxy)-3'-dimethoxymethyl-3'-ethoxycarbonylmethyl-hex-1'-enyl]-3-(2-hydroxy-ethyl)-6,7-dimethoxy-indole-1-carboxylic acid tert-butyl ester 
• 545363-02-8 (1'Z)-(3'S)-3-(2-acetoxy-ethyl)-2-[6'-(tert-butyldiphenyl-silanyloxy)-3'-dimethoxymethyl-3'-ethoxycarbonylmethyl-hex-1'-enyl]-6,7-dimethoxyindole-1-carboxylic acid tert-butyl ester 
• 545363-30-2 (1'Z)-(3'S)-2-[6'-(tert-butyldiphenyl-silanyloxy)-3'-dimethoxymethyl-3'-ethoxycarbonylmethyl-hex-1'-enyl]-6,7-dimethoxy-3-[2-(2-nitro-benzenesulfonylamino)-ethyl]-indole-1-carboxylic acid tert-butyl ester 
• 634911-98-1 ((3aR,10bS,12bS)-7,8-Dimethoxy-4-phenylsulfanyl-2,3,4,5,11,12-hexahydro-1H-6,12a-diaza-indeno[7,1-cd]fluoren-3a-yl)-acetic acid ethyl ester 
• 634912-05-3 (11R)-11-dimethylcarbamoylmethyl-11-formyl-1,2-dimethoxy-7-(2-nitro-benzenesulfonyl)-6,7,8,9,10,11,12,13-octahydro-5H-7,14-diazacycloundeca[a]indene-14-carboxylic acid tert-butyl ester 
• 634911-92-5 (11R)-11-dimethylcarbamoylmethyl-11-[1,3]dioxolan-2-yl-1,2-dimethoxy-7-(2-nitrobenzenesulfonyl)-6,7,8,9,10,11,12,13-octahydro-5H-7,14-diazacycloundeca[a]indene-14-carboxylic acid tert-butyl ester 
• 634912-20-2 (3S)-5-[3-(2-acetoxy-ethyl)-6,7-dimethoxy-1H-indol-2-yl]-3-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-3-[1,3]dioxolan-2-yl-pentanoic acid dimethylamide 
• 634911-89-0 (3S)-5-[3-(2-acetoxy-ethyl)-6,7-dimethoxy-1H-indol-2-yl]-3-[3-(tert-butyl-diphenyl-silanyloxy)-propyl]-3-[1,3]dioxolan-2-yl-pent-4-ynoic acid dimethylamide 
• 634911-97-0 3-(2-Acetoxy-ethyl)-2-[(Z)-(S)-3-dimethoxymethyl-3-ethoxycarbonylmethyl-6-(2-nitro-benzenesulfonylamino)-hex-1-enyl]-6,7-dimethoxy-indole-1-carboxylic acid tert-butyl ester 
• 634911-90-3 (3'S)-3-(2-acetoxy-ethyl)-2-[6'-(tert-butyl-diphenyl-silanyloxy)-3'-dimethylcarbamoylmethyl-3'-[1,3]dioxolan-2''-yl-hexyl]-6,7-dimethoxy-indole-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Enantioselective total synthesis of aspidophytine

(Matrix presented) An enantioselective total synthesis of aspidophytine is described. The indole fragment bearing a cis-alkene substituent was efficiently prepared through radical cyclization of a 2-alkenylphenylisocyanide followed by Sonogashira coupling of the generated 2-iodoindole derivative with a functionalized acetylene unit. After formation of the 11-membered cyclic amine, the aspidosperma skeleton and lactone ring were constructed to complete the total synthesis.