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5454-61-5

N-[(4-chlorophenyl)carbamoyl]butane-1-sulfonamide is a chemical compound with the molecular formula C11H15ClN2O3S. It is a derivative of butane-1-sulfonamide, featuring a 4-chlorophenylcarbamoyl group attached to the nitrogen atom. N-[(4-chlorophenyl)carbamoyl]butane-1-sulfonamide is known for its potential applications in pharmaceuticals, particularly as a precursor in the synthesis of certain drugs. Its structure combines the properties of a sulfonamide with those of a carbamate, which can lead to various biological activities. The presence of the chlorine atom on the phenyl ring can influence its reactivity and binding affinity to target proteins or enzymes. This chemical is an example of how functional group modifications can significantly alter the properties and uses of a molecule.

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  • 5454-61-5 Structure

  • Basic information

    1. Product Name: N-[(4-chlorophenyl)carbamoyl]butane-1-sulfonamide
    2. Synonyms:
    3. CAS NO:5454-61-5
    4. Molecular Formula: C11H15ClN2O3S
    5. Molecular Weight: 290.7664
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 5454-61-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.359g/cm3
    6. Refractive Index: 1.578
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-[(4-chlorophenyl)carbamoyl]butane-1-sulfonamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-[(4-chlorophenyl)carbamoyl]butane-1-sulfonamide(5454-61-5)
    11. EPA Substance Registry System: N-[(4-chlorophenyl)carbamoyl]butane-1-sulfonamide(5454-61-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 5454-61-5(Hazardous Substances Data)

5454-61-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5454-61-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5454-61:
(6*5)+(5*4)+(4*5)+(3*4)+(2*6)+(1*1)=95
95 % 10 = 5
So 5454-61-5 is a valid CAS Registry Number.

5454-61-5Downstream Products

5454-61-5Relevant articles and documents

Product-Derived Bimetallic Palladium Complex Catalyzes Direct Carbonylation of Sulfonylazides

Zhao, Jin,Li, Zongyang,Song, Shaole,Wang, Ming-An,Fu, Bin,Zhang, Zhenhua

supporting information, p. 5545 - 5549 (2016/05/09)

A novel product-derived bimetallic palladium complex catalyzes a sulfonylazide-transfer reaction with the σ-donor/π-acceptor ligand CO, and is advantageous given its broad substrate scope, high efficiency, and mild reaction conditions (atmospheric pressure of CO at room temperature). This methodology provides a new approach to sulfonylureas, which are present in both pharmaceuticals and agrochemicals. The synthesis of Glibenclamide on a gram scale further revealed the practical utility of this procedure. Mechanistically, the generation of a bridged bimetallic palladium species derived from the product sulfonylurea is disclosed as the crucial step for this catalytic cycle.

Antitumor compositions and methods of treatment

-

, (2008/06/13)

A method is provided for treating a susceptible neoplasm in mammals which comprises administering to a mammal in need of said treatment an effective amount for treating the neoplasm of the compound N-[[(4-chlorophenyl)amino]carbonyl]-1-butanesulfonamide or a pharmaceutically acceptable salt thereof, wherein said neoplasm is selected from the group consisting of ovarian, non-small cell lung, gastric, pancreatic, renal cell, breast, colorectal, small-cell lung, melanoma, head and neck, Kaposi's sarcoma, and rhabdomyosarcoma.

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