545401-38-5

Usage

Uses

Used in Pharmaceutical Synthesis:
Trans-bis(acetato)bis(tricyclohexylphosphine)palladium(II) is used as a catalyst for the synthesis of pharmaceuticals, enabling the formation of complex molecular structures that are crucial for the development of new drugs. Its selective and efficient catalytic properties are particularly valuable in the production of active pharmaceutical ingredients.
Used in Agrochemical Production:
In the agrochemical industry, trans-bis(acetato)bis(tricyclohexylphosphine)palladium(II) serves as a catalyst for the synthesis of various agrochemicals, including pesticides and herbicides. Its ability to facilitate carbon-carbon bond formation and coupling reactions is essential for creating the complex molecules required for effective crop protection agents.
Used in Material Science:
Trans-bis(acetato)bis(tricyclohexylphosphine)palladium(II) is utilized as a catalyst in the synthesis of advanced materials, such as polymers and composites, that exhibit unique properties for various applications. Its role in promoting selective and efficient reactions contributes to the development of innovative materials with improved performance characteristics.
Overall, trans-bis(acetato)bis(tricyclohexylphosphine)palladium(II) is a versatile and valuable catalyst in multiple industries, including pharmaceuticals, agrochemicals, and materials science, due to its ability to facilitate selective and efficient organic reactions.

Upstream product

• 3375-31-3 palladium diacetate 
• 2622-14-2 tricyclohexylphosphine 
• 3375-31-3 palladium diacetate 

Downstream Products

• 33309-88-5 palladium⁽⁰⁾bis(tricyclohexylphosphine) 

Relevant academic research and scientific papers

The impact of palladium(II) Reduction pathways on the structure and activity of palladium(0) catalysts

Two roads diverged: The mechanism of insitu PdII catalyst activation to generate an active {LnPd0} catalyst from an air-stable PdII precursor was examined using the standard conditions of a Miyaura borylation reaction. Two pathways for catalyst activation exist under these conditions, producing two structurally and chemically distinct {LnPd0} complexes (see scheme). Copyright

Reactivity studies of cationic palladium(II) phosphine carboxylate complexes with lewis bases: Substitution versus cyclometalation

Two classes of cationic palladium(II) phosphine carboxylate complexes were isolated and characterized. Reactions of trans-[(R3P) 2Pd(O2CR′)2] (1) with [Li(OEt 2)2.5][B(C6F5)4] in MeCN led to carboxylate abstraction and formation of trans-[(R3P) 2Pd(O2CR′)(MeCN)][B(C6F5) 4] (2) in good to excellent yields. On the other hand, carboxylate abstraction reactions of 1 with [Me2(H)NPh][B(C6F 5)4] or p-toluenesulfonic acid (HOTs·H 2O) in CH2Cl2 furnished the palladium cations [(R3P)2Pd(κ2-O,O-O2CR′)] + (3). The reactions of 2 and 3 with Lewis bases were found to be different in some cases. For example, reactions of 2 with pyridine furnished the simple products of acetonitrile substitution, trans-[(R3P) 2Pd(O2CR′)(py)][B(C6F5) 4]. In contrast, the reaction of 3e (R = iPr, R′ = CH3) with CD3CN in the presence of excess sodium carbonate yielded a material derived from cyclometalation of one of the iPr arms of iPr3P ligand. New complexes were characterized by elemental analyses and NMR (1H, 13C, and 31P) spectroscopic methods and in two cases by single-crystal X-ray structural methods.

Single component cationic palladium proinitiators for the latent polymerization of cycloolefins

Palladium compound compositions are provided in accordance with Formulae [((R)3E)aPd(Q)(LB)b]p [WCA]r, where ((R)3E) is a Group 15 electron donor ligand, Q is an anionic ligand, LB is a Lewis base, WCA is a weakly coordinating anion, a is 1, 2 or 3, b is 0, 1 or 2, the sum of a and b is 1, 2 or 3 and each of p and r is an integer such that the molecular charge is zero, or [(E(R)3)(E(R)2R*)Pd(LB)]p[WCA]r where E(R)2R* represents a Group 15 neutral electron donor ligand and where R* is an anionic hydrocarbyl containing moiety, bonded to the Pd and having a β hydrogen with respect to the Pd center. Such compound composition exhibits latent polymerization activity in the presence of polycyclic olefins.