545441-72-3Relevant academic research and scientific papers
Cyclic RGD peptides containing azabicycloalkane reverse-turn mimics
Belvisi, Laura,Caporale, Andrea,Colombo, Matteo,Manzoni, Leonardo,Potenza, Donatella,Scolastico, Carlo,Castorina, Massimo,Cati, Matilde,Giannini, Giuseppe,Pisano, Claudio
, p. 4353 - 4368 (2007/10/03)
The Fmoc-protected lactams 3 and 4 were used to prepare cyclo(Arg-Gly-Asp-lactam) 1 and cyclo(Arg-Gly-Asp-Phe-lactam) 2, which contain the Arg-Gly-Asp (RGD) recognition motif. Their solid-phase synthesis, conformational analysis, and binding to purified α
