54549-19-8

Basic information

• Product Name: beta-cis-2-(4-Chlorobenzhydryl)-3-quinuclidinol
• Synonyms: beta-cis-2-(4-Chlorobenzhydryl)-3-quinuclidinol;[2alpha(R*),3alpha]-2-[(4-Chlorophenyl)phenylmethyl]-1-azabicyclo[2.2.2]octan-3-ol
• CAS NO: 54549-19-8
• Molecular Formula: C₂₀H₂₂ClNO
• Molecular Weight: 327.8478
• Mol File: 54549-19-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 463.2°Cat760mmHg
• Flash Point: 233.9°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 2.24E-09mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: beta-cis-2-(4-Chlorobenzhydryl)-3-quinuclidinol(CAS DataBase Reference)
• NIST Chemistry Reference: beta-cis-2-(4-Chlorobenzhydryl)-3-quinuclidinol(54549-19-8)
• EPA Substance Registry System: beta-cis-2-(4-Chlorobenzhydryl)-3-quinuclidinol(54549-19-8)

Safety Data

• Hazardous Substances Data: 54549-19-8(Hazardous Substances Data)

Usage

General Description

Beta-cis-2-(4-Chlorobenzhydryl)-3-quinuclidinol, also known as Cisapride, is a medication used to treat gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD) and gastroparesis. It works by increasing the muscle contractions in the upper digestive tract, which helps to move food through the stomach and intestines more efficiently. This chemical is a member of the benzhydryl compounds, which are known for their antihistaminic and antiemetic properties. However, due to its potential for causing serious cardiac arrhythmias, Cisapride has been discontinued in some countries and is only available under restricted conditions. It is important to use this medication only under the supervision of a healthcare professional and to be aware of the potential risks and side effects.

InChI:InChI=1/C20H22ClNO/c21-17-8-6-15(7-9-17)18(14-4-2-1-3-5-14)19-20(23)16-10-12-22(19)13-11-16/h1-9,16,18-20,23H,10-13H2/t18?,19-,20+/m0/s1