Welcome to LookChem.com Sign In|Join Free
  • or
(2Z)-2-hydroxyimino-3-(4-nitrophenyl)propanoic acid, also known as nitisinone, is a pharmaceutical compound primarily used for the treatment of hereditary tyrosinemia type 1 (HT-1), a rare genetic metabolic disorder. It functions by inhibiting the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD), which plays a crucial role in the metabolism of the amino acid tyrosine. This inhibition helps to mitigate the accumulation of toxic byproducts in the body, thereby preventing the progression of HT-1. Nitisinone is typically administered orally in tablet form and has demonstrated efficacy in improving the long-term health outcomes for affected individuals. However, it is essential to use this medication under the guidance of a healthcare professional due to potential side effects.

5456-47-3

Post Buying Request

5456-47-3 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

5456-47-3 Usage

Uses

Used in Pharmaceutical Industry:
Nitisinone is utilized as a therapeutic agent for the treatment of hereditary tyrosinemia type 1 (HT-1), a rare genetic disorder characterized by the buildup of toxic metabolites due to the impaired breakdown of the amino acid tyrosine. By inhibiting the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD), nitisinone effectively reduces the accumulation of these toxic byproducts, thus preventing the progression of the disease and improving the long-term health outcomes for patients with HT-1.

Check Digit Verification of cas no

The CAS Registry Mumber 5456-47-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 6 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5456-47:
(6*5)+(5*4)+(4*5)+(3*6)+(2*4)+(1*7)=103
103 % 10 = 3
So 5456-47-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O5/c12-9(13)8(10-14)5-6-1-3-7(4-2-6)11(15)16/h1-4,14H,5H2,(H,12,13)/b10-8+

5456-47-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxyimino-3-(4-nitrophenyl)propanoic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5456-47-3 SDS

5456-47-3Upstream product

5456-47-3Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 5456-47-3