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4-Bromo-1,8-naphthyridine is a chemical compound with the molecular formula C8H5BrN2, characterized as a yellow crystalline solid. It is a member of the naphthyridine derivatives class and is recognized for its potential applications in various scientific fields.

54569-28-7

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54569-28-7 Usage

Uses

Used in Organic Synthesis:
4-Bromo-1,8-naphthyridine is utilized as a key intermediate in organic synthesis for the creation of a variety of chemical compounds, leveraging its unique structural properties to facilitate reactions and form new molecules.
Used in Medicinal Chemistry:
In the pharmaceutical industry, 4-Bromo-1,8-naphthyridine is used as a building block in the development of new drugs. Its structure contributes to the design of molecules with potential therapeutic effects, making it valuable in medicinal chemistry.
Used in Antimicrobial Applications:
4-Bromo-1,8-naphthyridine is studied for its potential antimicrobial properties, serving as a compound that could be incorporated into treatments to combat microbial infections.
Used in Antitumor Applications:
4-Bromo-1,8-naphthyridine is also being investigated for its antitumor properties, indicating its potential use in oncology for the development of cancer treatments.
Used in Coordination Chemistry:
4-Bromo-1,8-naphthyridine functions as a ligand in coordination chemistry, forming metal complexes that have been studied for their applications in various fields such as catalysis and materials science, broadening its utility in scientific research and industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 54569-28-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,5,6 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 54569-28:
(7*5)+(6*4)+(5*5)+(4*6)+(3*9)+(2*2)+(1*8)=147
147 % 10 = 7
So 54569-28-7 is a valid CAS Registry Number.

54569-28-7Relevant academic research and scientific papers

Method for preparing 4-bromo-1,8-naphthyridine

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Paragraph 0024; 0025, (2017/10/11)

The invention discloses a method for preparing 4-bromo-1,8-naphthyridine. The method comprises the following steps: taking 2-aminopyridine as an initial raw material, and performing cyclization, bromination and reduction to obtain the 4-bromo-1,8-naphthyridine. The compound is an important intermediate compound for research and development of new drugs.

Potential Antimalarials. I. 1,8-Naphthyridines

Barlin, Gordon B.,Tan, Weng-Lai

, p. 1065 - 1073 (2007/10/02)

A number of 1,8-naphthyridines including 8-aza analogues of chloroquine and amodiaquine, and similar 1,8-naphthyridines with 2- and 7-methyl substituents have been prepared.These compounds showed minimal antimalarial activity in a preliminary in vivo screen against Plasmodium vinckei vinckei.

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