5457-25-0 Usage
Description
Ethyl 2-cyano-2-nitroso-acetate is a chemical compound with the molecular formula C5H6N2O4. It is a yellow crystalline solid that is commonly used as a reagent in organic synthesis. Known for its versatile reactivity, it can undergo various chemical reactions to produce a wide range of compounds.
Uses
Used in Pharmaceutical Synthesis:
Ethyl 2-cyano-2-nitroso-acetate is used as a reagent for the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Synthesis:
In the agrochemical industry, ethyl 2-cyano-2-nitroso-acetate is utilized as a reagent for the synthesis of various agrochemicals, aiding in the production of substances that support agricultural processes.
Used in Fine Chemicals Synthesis:
Ethyl 2-cyano-2-nitroso-acetate is employed as a reagent in the synthesis of fine chemicals, which are important for a variety of specialized applications in different industries.
Used as a Precursor for Nitroso Compounds:
Due to its nitroso group, ethyl 2-cyano-2-nitroso-acetate is used as a valuable precursor for the synthesis of various nitroso compounds, which have applications in medicine and materials science.
It is important to handle ethyl 2-cyano-2-nitroso-acetate with care, as it may be hazardous if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 5457-25-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5457-25:
(6*5)+(5*4)+(4*5)+(3*7)+(2*2)+(1*5)=100
100 % 10 = 0
So 5457-25-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O3/c1-2-10-5(8)4(3-6)7-9/h4H,2H2,1H3
5457-25-0Relevant articles and documents
Synthesis process, intermediate and pharmaceutical process of 2, 4, 5-triamino-6-hydroxypyrimidine
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Paragraph 0032-0036, (2021/08/07)
The invention discloses a synthesis process of 2, 4, 5-triamino-6-hydroxypyrimidine, which comprises the following steps: 1) carrying out pressurized catalytic hydrogenation reaction on liquid 2-nitroso and 2-methyl cyanoacetate/ethyl cyanoacetate to generate 2-amino and 2-cyanoacetic acid methyl ester/ethyl ester; (2) carrying out cyclization reaction on the 2-amino, 2-methyl cyanoacetate/ethyl cyanoacetate and free guanidine to generate 2, 4, 5-triamino-6-hydroxypyrimidine; wherein the liquid 2-nitroso and 2-methyl cyanoacetate/ethyl cyanoacetate in the step 1) are generated by carrying out nitrosation reaction on methyl cyanoacetate/ethyl cyanoacetate and sodium nitrite. The invention also discloses intermediates 2-nitroso and 2-methyl cyanoacetate in the synthesis process, a synthesis process of the intermediates, and a pharmaceutical process taking the 2, 4, 5-triamino-6-hydroxypyrimidine as an intermediate. According to the present invention, the liquid new compounds such as 2-nitroso and 2-methyl cyanoacetate/ethyl cyanoacetate are subjected to the catalytic hydrogenation reaction, such that the problems of large water consumption and large wastewater yield in the 2, 4, 5-triamino-6-hydroxypyrimidine synthesis process can be solved, and the great economic significance and the great environmental protection significance are provided.
