54609-74-4

Upstream product

• 54609-27-7 1,3,4,6,6-pentamethyl-2-phenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrrole-4-carbonitrile 

Downstream Products

• 54610-36-5 2-phenyl-2,4,5,6-tetrahydro-1,4,6,6-tetramethylcyclopentapyrrole-4-carboxylic acid 
• 54610-34-3 1-hydroxymethyl-4,6,6-trimethyl-2-phenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrrole-4-carboxylic acid amide 
• 54610-37-6 2-phenyl-2,4,5,6-tetrahydro-1,4,6,6-tetramethylcyclopentapyrrole-4-carboxamide 
• 54610-29-6 2-phenyl-1-formyl-2,4,5,6-tetrahydro-4,6,6-trimethylcyclopenta[c]-pyrrole-4-carboxamide 
• 54609-78-8 1-formyl-2-phenyl-2,4,5,6-tetrahydro-4,6,6-tetramethylcyclopentapyrrole-4-carbonitrile 
• 54609-75-5 4-cyano-1-formyl-2,4,5,6-tetrahydro-4,6,6-tetramethylcyclopentapyrrole-3-carboxylic acid 

Relevant academic research and scientific papers

Experimental anti-ulcer drugs. IV 1,3-Disubstituted 2,4,5,6-tetrahydro-4,6,6-trimethyl-2-phenylcyclopenta[c]pyrrole-4-carboxamides

The synthesis of 1,3-disubstituted 2,4,5,6-tetrahydro-4,6,6-trimethyl-2-phenylcyclopenta[c]pyrrole-4-carboxamides is reported. The derivatives included R1 = R3 = H, R1 = CH2OH with R3 = H (16)(C1

Cyclopenta[c]pyrrole derivatives

2,4,5,6-Tetrahydrocyclopenta[c]pyrrole-4-carboxamide and 4-thiocarboxamide derivatives useful as anti-secretory and anti-ulcer agents are prepared by hydrolysis or thiohydrolysis of the corresponding 2,4,5,6-tetrahydrocyclopenta[c]pyrrole-4-carbonitriles or, in the case of the thiocarboxamides, by reaction of the 4-carboxamide with phosphorus pentasulfide.