546093-45-2

Usage

Uses

Used in Pharmaceutical Industry:
(R)-4-(1-hydroxy-ethyl)-piperidine is used as a building block for the synthesis of various pharmaceuticals and biologically active compounds. Its unique structure and stereochemistry make it a valuable component in the development of new drugs with specific therapeutic targets.
Used in Medicinal Chemistry:
(R)-4-(1-hydroxy-ethyl)-piperidine is used as a key intermediate in the design and synthesis of novel compounds with potential therapeutic applications. Its hydroxyethyl group and stereochemistry allow for the creation of molecules with tailored properties, such as improved binding affinity, selectivity, and pharmacokinetic profiles.
Used in Organic Synthesis:
(R)-4-(1-hydroxy-ethyl)-piperidine serves as a versatile starting material for the synthesis of a wide range of organic compounds, including those with potential applications in various industries such as pharmaceuticals, agrochemicals, and materials science. Its reactivity and functional group compatibility make it a useful component in the development of new synthetic routes and methodologies.

Upstream product

• 27854-88-2 (R)-1-(4-pyridinyl)ethanol 

Relevant academic research and scientific papers

CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS

Therapeutic compounds are disclosed having the general formula (I) that are useful for the treatment of metabolic disorders, including type II diabetes. The compounds have activity as agonists of GPR119. Compounds having the stereochemistry of formula (la) may also demonstrate DPP-IV inhibitory activity.

BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS

The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.

Ester derivatives

This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); 1[in which A signifies a group expressed by a formula (a0) or (b0); 2Ar signifies optionally substituted aryl or heteroaryl; B1 and B2 signify aliphatic hydrocarbon; R1 signifies fluorine-substituted cycloalkyl; R2, R3 and R4 signify lower alkyl, single bond or alkylene bonded to B1, or R2 and R3 are united to signify alkylene; R5 and R7 signify hydrogen, lower alkyl, or a single bond or alkylene bonded to B2; R6 signifies hydrogen, lower alkyl or a group expressed as —N(R8)R9; and X?signifies an anion].