5463-65-0 Usage
Chemical class
2-(3-methylbenzyl)-1H-benzimidazole belongs to the benzimidazole class of compounds.
Molecular weight
The molecular weight of 2-(3-methylbenzyl)-1H-benzimidazole is 207.27 g/mol.
Pharmaceutical industry use
2-(3-methylbenzyl)-1H-benzimidazole is commonly used in the pharmaceutical industry as a potential drug candidate due to its various biological activities.
Biological activities
2-(3-methylbenzyl)-1H-benzimidazole has anti-cancer, anti-inflammatory, and anti-bacterial properties.
Unique structure and properties
The unique structure and properties of 2-(3-methylbenzyl)-1H-benzimidazole make it an important molecule for the development of new drugs and therapeutics.
Research studies
2-(3-methylbenzyl)-1H-benzimidazole is also used in research studies to further understand its potential applications and mechanisms of action in biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 5463-65-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5463-65:
(6*5)+(5*4)+(4*6)+(3*3)+(2*6)+(1*5)=100
100 % 10 = 0
So 5463-65-0 is a valid CAS Registry Number.
5463-65-0Relevant academic research and scientific papers
Synthesis and antimicrobial activity of some new triazole bridged benzimidazole substituted phthalonitrile and phthalocyanines
Kantar, Günay Kaya,Mente?e, Emre,Beri?, Fatih ?aban,?a?maz, Selami,Kahveci, Bahittin
, p. 59 - 65 (2018/03/02)
In this study, some new phthalonitriles and metallophthalocyanines (Zn, Ni, Co, and Cu) containing triazole bridged benzimidazole moieties were synthesized starting from 2-(3-methylbenzyl)-1H-benzimidazole. Newly synthesized compounds have been tested for their antimicrobial effects against four Gram positively (Bacillus cereus 702 Roma, B. megaterium DSM-32, B. subtilis ATCC 6633, and Staphylococcus aureus ATCC 25923) and four Gram negatively (Escherichia coli ATCC 25922, Enterobacter cloaceae ATCC13047, Pseudomonas aeruginosa ATCC 27853, and Yersinia pseudotuberculosis ATCC 911) bacteria. According to results, compounds 6, 7b, 7c, and 8a have the best activity with MIC values of 31.25 μg/mL to B. subtilis. The second best activity belongs to compounds 4, 5, 7, 8, 7a, 8c, and 8d with the MIC value of 62.5 μg/mL on the same bacterium. Zinc (II) phthalocyanines have better antimicrobial activity than other metallophthalocyanines against Gram (+) bacteria.
