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2-(4-methylphenyl)quinolin-3-amine is an organic compound with the molecular formula C16H14N2. It is a derivative of quinoline, a heterocyclic aromatic compound with a benzene ring fused to a pyridine ring. The molecule features a 4-methylphenyl group attached to the quinoline core at the 2-position and an amino group at the 3-position. 2-(4-methylphenyl)quinolin-3-amine is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as a building block for the development of new drugs. Its chemical structure and properties make it a versatile intermediate in organic synthesis, allowing for further functionalization and the creation of a range of compounds with different biological activities.

5463-88-7

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5463-88-7 Usage

Structure

Quinoline derivative with a 4-methylphenylamino group on the 2-position of the quinoline ring

Potential applications

Pharmaceutical industry for anti-inflammatory and anticancer properties, development of novel drugs for the treatment of various diseases

Usage

Building block in organic synthesis and research activities

Unique attributes

Unique chemical structure and reactivity

Check Digit Verification of cas no

The CAS Registry Mumber 5463-88-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,6 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5463-88:
(6*5)+(5*4)+(4*6)+(3*3)+(2*8)+(1*8)=107
107 % 10 = 7
So 5463-88-7 is a valid CAS Registry Number.

5463-88-7Relevant academic research and scientific papers

Modular Synthesis of Polysubstituted Quinolin-3-amines by Oxidative Cyclization of 2-(2-Isocyanophenyl)acetonitriles with Organoboron Reagents

Wang, Shihui,Xu, Jian,Song, Qiuling

, p. 6789 - 6794 (2021/09/02)

Polysubstituted quinolin-3-amines are vital structural motifs because of their broad biological activities as well as versatile transformational abilities. However, they are not easily accessible. We disclose a protocol with Mn(III) acetate as a mild one-

Chiral phosphoric acid-catalyzed asymmetric transfer hydrogenation of quinolin-3-amines

Cai, Xian-Feng,Guo, Ran-Ning,Feng, Guang-Shou,Wu, Bo,Zhou, Yong-Gui

supporting information, p. 2680 - 2683 (2014/06/09)

A chiral phosphoric acid catalyzed asymmetric transfer hydrogenation of aromatic amines, quinolin-3-amines, was successfully developed with up to 99% ee. To supplement our previous work on the Ir-catalyzed asymmetric hydrogenation of 2-alkyl substituted q

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