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3-amino-5-chloro-6-methylpyrazine-2-carbonitrile is a chemical compound with the molecular formula C6H5ClN4. It is a derivative of pyrazine, a heterocyclic compound consisting of a six-membered aromatic ring containing two nitrogen atoms. This specific compound features a chlorine atom at the 5th position, a methyl group at the 6th position, an amino group at the 3rd position, and a nitrile group at the 2nd position. It is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and reactivity. The compound is also of interest in the field of organic chemistry for its ability to participate in various chemical reactions, such as nucleophilic substitutions and cycloadditions, making it a valuable building block for the creation of more complex molecules.

54632-08-5

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54632-08-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 54632-08-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,6,3 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 54632-08:
(7*5)+(6*4)+(5*6)+(4*3)+(3*2)+(2*0)+(1*8)=115
115 % 10 = 5
So 54632-08-5 is a valid CAS Registry Number.

54632-08-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-amino-5-chloro-6-methylpyrazine-2-carbonitrile

1.2 Other means of identification

Product number -
Other names 3-AMINO-5-CHLORO-6-METHYLPYRAZINECARBONITRILE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54632-08-5 SDS

54632-08-5Relevant academic research and scientific papers

Discovery of pyrazol-3-ylamino pyrazines as novel JAK2 inhibitors

Ioannidis, Stephanos,Lamb, Michelle L.,Davies, Audrey M.,Almeida, Lynsie,Su, Mei,Bebernitz, Geraldine,Ye, Minwei,Bell, Kirsten,Alimzhanov, Marat,Zinda, Michael

scheme or table, p. 6524 - 6528 (2010/05/18)

The design, synthesis and biological evaluation of a series of pyrazol-3-ylamino pyrazines as potent and selective JAK2 kinase inhibitors is reported, along with the pharmacokinetic and pharmacodynamic properties of lead compounds.

PYRAZOLYL-AMINO-SUBSTITUTED PYRAZINES AND THEIR USE FOR THE TREATMENT OF CANCER

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Page/Page column 71-72, (2008/12/04)

The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These novel compounds provide a treatment for myeloproliferative disorders and cancer.

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