5465-20-3

Usage

Uses

Used in Pharmaceutical Industry:
5-Hexylbenzene-1,3-diol is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Cosmetics Industry:
5-Hexylbenzene-1,3-diol is used as an additive in the cosmetics industry, where it serves as a skin conditioning agent and emollient. Its ability to form hydrogen bonds with the skin's proteins and lipids helps to improve skin hydration and maintain its natural moisture balance.
Used in Chemical Synthesis:
5-Hexylbenzene-1,3-diol is used as a starting material for the synthesis of various organic compounds, including dyes, polymers, and other specialty chemicals. Its reactive hydroxyl groups make it an attractive candidate for further functionalization and modification.
Used in Antimicrobial Applications:
5-Hexylbenzene-1,3-diol has been found to possess antimicrobial properties, making it a potential candidate for use in the development of new antimicrobial agents. Its ability to disrupt bacterial cell membranes and inhibit essential cellular processes could lead to the creation of novel antibiotics and antifungal agents.
Used in Material Science:
5-Hexylbenzene-1,3-diol can be used in the development of new materials with specific properties, such as improved thermal stability, mechanical strength, or chemical resistance. Its unique structure and reactivity make it a valuable component in the design and synthesis of advanced materials for various applications, including electronics, automotive, and aerospace industries.

Synthesis Reference(s)

The Journal of Organic Chemistry, 37, p. 2901, 1972 DOI: 10.1021/jo00983a025

Upstream product

• 41497-45-4 1-hexyl-3,5-dimethoxy-benzene 
• 21406-61-1 pentyltriphenylphosphonium bromide 
• 17213-57-9 3,5-dimethoxybenzoyl chloride 
• 1132-21-4 3,5-dimethoxybenzoic acid 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 102342-63-2 2,4-dihydroxy-6-n-hexylbenzoic acid, methyl ester 
• 34993-70-9 6-Hexyl-2,4-dihydroxybenzoesaeureaethylester 
• 70336-34-4 2-Bromo-5-hexyl-3-hydroxy-cyclohex-2-enone 

Downstream Products

• 56694-86-1 MB₁_D_665987A-4 
• 117-51-1 (R)-3-hexyl-6,6,9-trimethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-1-ol 

Relevant academic research and scientific papers

Using (+)-carvone to access novel derivatives of (+)-ent-cannabidiol: The first asymmetric syntheses of (+)-ent-CBDP and (+)-ent-CBDV

(?)-Cannabidiol [(?)-CBD] has recently gained prominence as a treatment for neuro-inflammation and other neurodegenerative disorders; interest is also developing in its synthetic enantiomer, (+)-CBD, which has a higher affinity to CB1/CB2 receptors than the natural stereoisomer. We have developed an inexpensive, stereoselective route to access ent-CBD derivatives using (+)-carvone as a starting material. In addition to (+)-CBD, we report the first syntheses of (+)-cannabidivarin, (+)-cannabidiphorol as well as C-6/C-8 homologues.

Biosynthesis of primin and miconidin and its derivatives

Numerous 2-methoxy-6-n-alkyl-1,4-benzoquinones with interesting biological activities have been found as constituents of plants and plant seeds. The most prominent is primin, the n-pentyl derivative, which is stored in trichomes on leaves and stems of Primula obconica and is responsible for primrose dermatitis. The biosynthesis of primin was studied by feeding experiments with radioactively labelled precursors and unlabelled homologues. Copyright

BIOLOGICALLY ACTIVE PHENOLIC METABOLITES OF A VERTICICLADIELLA SPECIES

The metabolites produced when a Verticicladiella species (Canadian Forestry Service strain C728), the causative agent of the black stain root disease of many conifers, is grown in liquid culture have been investigated.Orcinol, orcinol monomethyl ether, 1,3,6,8-tetrahydroxyanthraquinone, and the α-L-rhamnopyranosides of orcinol and orcinol methyl ether have been isolated and indentified.Orcinol methyl ether and its rhamnoside both show antibacterial activity and orcinol methyl ether also inhibits the growth of pine germlings.The general antibacterial activity of 5-alkylresorcinols and their monomethyl ethers is reported.-Key Word Index-Verticicladiella sp.; Deuteromycontina; blue-stain fungus; phytotoxin; phenols; methylorcinol rhamnoside; phenol monomethyl ethers; antiseptics.