54658-03-6Relevant articles and documents
Asymmetric dihydroxylation of disubstituted allenes
Fleming, Steven A.,Liu, Renmao,Redd, J. Ty
, p. 8095 - 8098 (2007/10/03)
Asymmetric dihydroxylation of 1,1-disubstituted and 1,3-disubstituted allenes can be used to synthesize chiral α-hydroxy ketones. We have also obtained α,α′-dihydroxy ketones with high enantioselectivity from 1,3-disubstituted allenes. Low conversion of the dihydroxylation of chiral allenes can be used as a kinetic resolution of sterically hindered allenes.