54661-55-1 Usage
Benzimidazole derivative
The compound is based on a benzimidazole structure, which is a heterocyclic aromatic organic compound.
Chloropyridine moiety
The compound contains a chlorine atom attached to a pyridine ring, which is a six-membered aromatic ring.
Antimicrobial and antifungal activities
The compound has been shown to inhibit the synthesis of nucleic acids in microorganisms, making it effective against bacteria and fungi.
Potential anticancer activities
The compound has been shown to induce cell cycle arrest and apoptosis in cancer cells, suggesting its potential as an anti-cancer agent.
Therapeutic applications
The compound has attracted interest in pharmaceutical research for its potential use in treating infections and cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 54661-55-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,6,6 and 1 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54661-55:
(7*5)+(6*4)+(5*6)+(4*6)+(3*1)+(2*5)+(1*5)=131
131 % 10 = 1
So 54661-55-1 is a valid CAS Registry Number.
54661-55-1Relevant articles and documents
2-heteroaryl benzimidazole derivatives as melanin concentrating hormone receptor 1 (MCH-R1) antagonists
Lim, Chae Jo,Kim, Jeong Young,Lee, Byung Ho,Oh, Kwang-Seok,Yi, Kyu Yang
, p. 2305 - 2310 (2013/09/24)
A novel series of 2-heteroaryl substituted benzimidazole derivatives, containing the piperidinylphenyl acetamide group at the 1-position, were synthesized and evaluated as MCH-R1 antagonists. Extensive SAR investigation probing the effects of C-2 heteroaryl group led to the identification of 2-[2-(pyridin-3-yl)ethyl] analog 3o, which exhibits highly potent MCH-R1 binding activity with an IC50 value of 1 nM. This substance 3o also has low hERG binding activity, good metabolic stability, and favorable pharmacokinetic properties.
