54671-66-8

Basic information

• Product Name: 1H-1,2,4-Triazole-3-carboxamide,5-chloro-(9CI)
• Synonyms: 1H-1,2,4-Triazole-3-carboxamide,5-chloro-(9CI);3-chloro-1H-1,2,4-triazole-5-carboxamide(SALTDATA: FREE)
• CAS NO: 54671-66-8
• Molecular Formula: C3H3ClN4O
• Molecular Weight: 146.53512
• Product Categories: AMIDE
• Mol File: 54671-66-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-1,2,4-Triazole-3-carboxamide,5-chloro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,4-Triazole-3-carboxamide,5-chloro-(9CI)(54671-66-8)
• EPA Substance Registry System: 1H-1,2,4-Triazole-3-carboxamide,5-chloro-(9CI)(54671-66-8)

Safety Data

• Hazardous Substances Data: 54671-66-8(Hazardous Substances Data)

Usage

Class

1H-1,2,4-Triazole derivatives

Structure

A 5-chloro derivative with a carboxamide group attached to the triazole ring

Biological activities

Antimicrobial, antifungal, and anticancer properties

Potential uses

Developing new drugs for various medical applications

Additional notes

Further research is needed to fully understand its potential uses, but holds promise for medicinal and pharmaceutical purposes.

Upstream product

• 21733-05-1 methyl 5-chloro-1,2,4-triazole-3-carboxylate 

Relevant articles and documents

Chemoenzymatic method of 1,2,4-triazole nucleoside synthesis: Possibilities and limitations

Possibilities and limitations of chemoenzymatic synthesis of novel structural analogues of an antiviral preparation of Ribavirin (1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were established. A synthesis of various amides of 1H-1,2,4-triazole-3-carboxylic acid and its 5-substituted analogues - potential substrates of purine nucleoside phosphorylase - has been described. Comparative efficiency of preparation methods of these amides, as well as the methods of introduction of functional groups to the C5 position of heterocyclic system, were investigated. Novel analogues of Ribavirin containing various substitutes in the carboxamide group were synthesized. A biotechnological method was developed for the preparation of 1-β-D-ribofuranozyl-1,2,4-triazole-3-carbonitryl, an intermediate in the synthesis of Viramidine, the modern analogue of Ribavirin.