54675-49-9

Usage

Uses

Used in Cancer Therapy:
8-Bromo-3-nitroquinoline-2,4-diol is used as an antineoplastic agent for its ability to reduce the viability of cancer cells. It has demonstrated effectiveness in inhibiting the growth and proliferation of various cancer types.
Used in Radiosensitization:
8-Bromo-3-nitroquinoline-2,4-diol is used as a radiosensitizing agent to enhance the effectiveness of radiation treatment in cancer therapy. It has the potential to increase the sensitivity of cancer cells to radiation, leading to improved therapeutic outcomes.
Used in Drug Development:
8-Bromo-3-nitroquinoline-2,4-diol is used as a research chemical in the development of new anticancer drugs. Its unique properties and potential applications in cancer therapy make it a valuable compound for further investigation and exploration in the field of oncology.

Upstream product

• 54675-27-3 8-bromo-4-hydroxy-2-quinolone 

Relevant academic research and scientific papers

ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES

Aryl substituted imidazoquinoline compounds, according to formula I, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing w or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral., and neoplastic, are disclosed. formula (I): wherein: R is selected from the group consisting of alkyl, alkoxy, hydroxy, and trifluoromethyl;. N is 0 or 1; R3 is selected from the group consisting of: -Z-Ar,-Z-Ar’-Y-R4, -Z-Ar’-X-Y-R4, Z-Ar’-R5, and-Z-Ar'-X-R5; Ar is selected from the group consisting of aryl and heteroaryl both of which can be unsubstituted or can be substituted by one or more substituents independently selected from the group consisting of alkyl, alkenyl, alkoxy, methylenedioxy, haloalkyl, haloalkoxy, halogen, nitro, hydroxy, hydroxyalkyl, mercapto, cyano, carboxy, formyl, aryl, aryloxy, arylalkoxy, heteroaryl, heteroaryloxy, heteroarylalkoxy; heterocyctyl, heterocyclylalkyl, amino, alkylamino, and dialkylamino.

Anti-allergenic carbostyril derivatives

A class of 4-hydroxy-3-nitroearbostyril derivatives are useful in the inhibition of certain types of antigen antibody reactions.