5468-77-9

Basic information

• Product Name: 2-Bromo-N,N-dimethylacetamide
• Synonyms: 2-Bromo-N,N-dimethylacetamide;2-bromo-N,N-dimethyl-ethanamide;N,N-dimethyl-bromoacetamide;2-BROMO-N,N-DIMETHYLACETAMIDE 95%
• CAS NO: 5468-77-9
• Molecular Formula: C₄H₈BrNO
• Molecular Weight: 166.01642
• Mol File: 5468-77-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 72-73 °C(Solv: toluene (108-88-3))
• Boiling Point: 190.4°Cat760mmHg
• Flash Point: 68.9°C
• Appearance: /
• Density: 1.48g/cm³
• Vapor Pressure: 0.402mmHg at 25°C
• Refractive Index: 1.48
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.04±0.70(Predicted)
• CAS DataBase Reference: 2-Bromo-N,N-dimethylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-N,N-dimethylacetamide(5468-77-9)
• EPA Substance Registry System: 2-Bromo-N,N-dimethylacetamide(5468-77-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5468-77-9(Hazardous Substances Data)

Usage

General Description

2-Bromo-N,N-dimethylacetamide is a chemical compound often used as a functional reagent in scientific research and laboratory applications. It is an acetamide in which an acetyl group is substituted at a position by bromine and two methyl groups. 2-Bromo-N,N-dimethylacetamide has a molar mass of approximately 198.02 g/mol. Generally available in solid form, this chemical should be handled and stored carefully due to its potential reactivity and hazardous characteristics. As a research compound, 2-Bromo-N,N-dimethylacetamide is primarily utilized in the pharmaceutical industry for synthesis purposes and other organic chemical reactions.

InChI:InChI=1/C5H10BrNO/c1-4(6)5(8)7(2)3/h4H,1-3H3

Downstream Products

• 58264-47-4 Cyclopropanecarboxylic acid (2,6-diethyl-phenyl)-dimethylcarbamoylmethyl-amide 
• 132930-12-2 1-(N,N-dimethylcarbamoylmethyl)-4,7,10-tris-(4-tolylsulphonyl)-1,4,7,10-tetraazacyclododecane 
• 123059-51-8 2-[tert-Butylsulfanyl-(4-chloro-phenyl)-methylsulfanyl]-N,N-dimethyl-acetamide 
• 123059-50-7 2-[(4-Chloro-phenyl)-nonylsulfanyl-methylsulfanyl]-N,N-dimethyl-acetamide 
• 156221-88-4 4'-<<4,5-dihydro-5-<(N,N-dimethylcarbamoyl)methyl>-2-ethyl-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl>methyl>biphenyl-2-carbonitrile 
• 156221-89-5 4'-<<2-cyclopropyl-4,5-dihydro-5-<(N,N-dimethylcarbamoyl)methyl>-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl>methyl>biphenyl-2-carbonitrile 
• 156221-87-3 4'-<<4,5-dihydro-5-<(N,N-dimethylcarbamoyl)methyl>-4-oxo-2-propyl-3H-imidazo<4,5-c>pyridin-3-yl>methyl>biphenyl-2-carbonitrile 
• 156221-86-2 4'-<<2-butyl-4,5-dihydro-5-<(N,N-dimethylcarbamoyl)methyl>-4-oxo-3H-imidazo<4,5-c>pyridin-3-yl>methyl>biphenyl-2-carbonitrile 
• 160446-31-1 N,N-dimethyl-2-<<(1-hydroxycyclohexyl)methyl>amino>acetamide 
• 160937-99-5 N,N-dimethyl-2-<<1(S)-phenylethyl>amino>acetamide 
• 78698-19-8 α-(phenylthio)-N,N-dimethylacetamide 
• 832151-55-0 2-[2-benzyloxy-1-ethyl-6-(tetrahydro-pyran-2-yloxy)-hex-4-enyloxy]-N,N-dimethyl-acetamide 
• 194785-64-3 (-)-2-[(2S)-2-[[(2R)-2-[4-Benzyloxy-3-(2-benzyloxyethyl)-phenyl]-2-hydroxyethyl]amino]-1,2,3,4-tetrahydronaphthalen-7-yloxy]-N,N-dimethylacetamide 

Relevant articles and documents

Aminocyclopentane esters and pharmaceutical formulations

Compounds are described of the formulae (1a) and (1b) STR1 in which: --COR1 is an ester group, n is 1 or 2, W is C1-7 alkylene, X is cis or trans --CH=CH or --CH2 CH2 --, Y is a saturated heterocyclic amino group, R2 is substituted or unsubstituted phenylalkyl, thienylalkyl or naphthylalkyl or cinnamyl, and R3 is --H or C1-5 alkanoyl, including their salts. These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic or antiasthmatic agents.