54682-95-0Relevant academic research and scientific papers
Concise and regioselective synthesis of 5H-imidazo[1,2-e][1,3,5]triazepines
Demydchuk, Bohdan A.,Mykhalchenko, Oleksandr A.,Rusanov, Eduard B.,Moskvina, Viktoriia S.,Brovarets, Volodymyr S.
, (2022/03/27)
In this communication, we report a regioselective synthesis of novel 5H-imidazo[1,2-e][1,3,5]triazepines via the interaction of tetrachloro-2-aza-1,3-butadienes with (1H-imidazol-2-yl)methanamine. The advantages of the presented method are mild reaction conditions, a simple work-up procedure, available reagents, and high yields. A possible mechanism is proposed for the synthesis of key products. The structure of one of the obtained products was proven with asingle crystal X-ray diffraction-based structure.
A new, high-yield synthesis of 3-aryl-1,2,4-triazoles
Guirado, Antonio,López-Caracena, Libertad,López-Sánchez, José I.,Sandoval, José,Vera, María,Bautista, Delia,Gálvez, Jesús
, p. 8055 - 8060 (2016/11/19)
A convenient new synthetic approach to 3-aryl-1,2,4-triazoles has been developed. Chloralamides were obtained by high yield reactions between benzamides and chloral hydrate. These reacted with a phosphorus pentachloride/phosphorus oxychloride mixture unde
