54683-86-2Relevant academic research and scientific papers
Ni-catalyzed cross-electrophile coupling of α-hydroxy carbonyl compound-derived oxalates with vinyl triflates
Tao, Xianghua,Yao, Ken,Xue, Weichao
, (2021)
A nickel-catalyzed reductive vinylation of α-hydroxy carbonyl compound-derived C–O electrophiles to access β,γ-unsaturated carbonyl compounds is reported here. By this method, a library of vinyl triflates can serve as vinylating reagents, while various alkyl oxalates undergo C–O bond fragmentation to provide α-carbonyl radicals. This work expands the scope of cross-electrophile coupling reactions that employ two low toxic C–O electrophiles as coupling partners.
COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS
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Page/Page column 622, (2015/02/02)
The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
O-SILYLATED ENOLATES IN ORGANIC SYNTHESIS: SULPHUR-MEDIATED ALKYLATION OF ESTERS WITH ALKENES.
Patel, Shailesh K.,Paterson, Ian
, p. 1315 - 1318 (2007/10/02)
O-Silylated ester enolates can be alkylated, under ZnBr2-catalysis, by the PhSCl-adducts of mono- and di-substituted alkenes to give γ-phenylthioesters, from which sulphur can be removed both reductively and oxidatively.This alkene carbosulphenylation rea
