54684-83-2 Usage
Uses
Polyguanylic acid potassium salt has been used:as a ligand for surface neuropilin-1 (NRP1) for internalization studiesfor intercalation studies with trisubstituted and disubstituted triazole-linked phenyl derivatives CL41, CL42 and CL2r50 using voltammetry methodas a synthetic polynucleotide for agarose gel electrophoresis analysis
General Description
Polyguanylic acid takes up a four-stranded helical structure. It is synthetically produced in Thermus thermophilus from guanosine diphosphate (GDP) and its synthesis is catalyzed by the enzyme polynucleotide phosphorylase.
Biochem/physiol Actions
Polyguanylic acid acts as a ligand for scavenger receptor and reduces the surface expression neuropilin-1 in endothelial cells.
Check Digit Verification of cas no
The CAS Registry Mumber 54684-83-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,6,8 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 54684-83:
(7*5)+(6*4)+(5*6)+(4*8)+(3*4)+(2*8)+(1*3)=152
152 % 10 = 2
So 54684-83-2 is a valid CAS Registry Number.