54699-41-1Relevant articles and documents
Mercuric triflate-TMU catalyzed hydration of terminal alkyne to give methyl ketone under mild conditions
Nishizawa, Mugio,Skwarczynski, Mariusz,Imagawa, Hiroshi,Sugihara, Takumichi
, p. 12 - 13 (2002)
Herein developed mercuric triflate-TMU catalyzed hydration of terminal alkyne is a mild procedure to give methyl ketone in excellent yield with high chemoselectivity. By using 0.05 eq of Hg(OTf)2·(TMU)2 and 3 eq of water, hydration takes place at a reasonable rate in acetonitrile.