547-96-6 Usage
Uses
Used in Medical Diagnostics:
3,7,12-Trihydroxycoprostane is used as a biomarker for the detection and monitoring of liver function and bile salt synthesis. Its accumulation in urine can indicate the presence of jaundice or Xanthomatosis, aiding in the diagnosis and treatment of these conditions.
Used in Pharmaceutical Research:
As a substrate for the sterol 27-hydroxylase enzyme, 3,7,12-trihydroxycoprostane is utilized in pharmaceutical research to study the mechanisms of bile salt synthesis and its regulation. This knowledge can contribute to the development of new therapeutic agents for liver-related disorders and other conditions influenced by bile salt metabolism.
Check Digit Verification of cas no
The CAS Registry Mumber 547-96-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 547-96:
(5*5)+(4*4)+(3*7)+(2*9)+(1*6)=86
86 % 10 = 6
So 547-96-6 is a valid CAS Registry Number.
InChI:InChI=1/C27H48O3/c1-16(2)7-6-8-17(3)20-9-10-21-25-22(15-24(30)27(20,21)5)26(4)12-11-19(28)13-18(26)14-23(25)29/h16-25,28-30H,6-15H2,1-5H3/t17-,18+,19-,20-,21+,22+,23-,24+,25+,26+,27-/m1/s1
547-96-6Relevant academic research and scientific papers
Facial amphiphiles and methods of use
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Page/Page column 57, (2015/07/27)
The invention provides amphiphilic compounds with hydrophobic and hydrophilic faces. The compounds can be readily prepared from steroids such as cholic acid or deoxycholic acid, which provide hydrophobic skeletons with structures similar to that of the li
Rapid hydrogenation of unsaturated sterols and bile alcohols using microwaves
Dayal,Ertel,Rapole,Asgaonkar,Salen
, p. 451 - 454 (2007/10/03)
This paper describes an operationally simple, rapid hydrogenation of unsaturated sterols and bile alcohols in a domestic microwave oven. This has been achieved by the addition of catalytic amounts of Pd/C in methylene chloride/propylene glycol solvents in the presence of ammonium formate followed by microwave irradiation. It is suggested that this methodology will be helpful in the identification of saturated and unsaturated sterols with different side-chain structures in rare diseases: sitosterolemia, cerebrotendinous xanthomatosis (CTX), as well as atherosclerosis and diabetes mellitus. Sterols, such as cholesterol, campesterol, sitosterol, and bile alcohols with unsaturated side chains, were converted to their reduced congeners with high yield and purity.
