54705-42-9

Basic information

• Product Name: (S)-(-)-4-TERT-BUTYL-2-OXAZOLIDINONE
• Synonyms: (4S)-4-tert-Butyl-2-oxazolidinone;(S)-(-)-4-T-BUTYL-2-OXAZOLIDINONE;(S)-4-T-BUTYL-2-OXAZOLIDINONE;(S)-4-(1,1-DIMETHYL)-2-OXAZOLIDINONE;(S)-(-)-4-TERT-BUTYL-2-OXAZALIDINONE;(S)-(-)-4-TERT-BUTYL-2-OXAZOLIDINONE;(S)-(+)-4-TERT-BUTYL-2-OXAZOLIDINONE;(S)-4-TERT-BUTYL-2-OXAZOLIDINONE
• CAS NO: 54705-42-9
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18
• Product Categories: Oxazolidinone;Chiral Reagent;Amino Alcohols & Deriv.;CHIRAL CHEMICALS
• Mol File: 54705-42-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 118-120 °C(lit.)
• Boiling Point: 289.1 °C at 760 mmHg
• Flash Point: 128.6 °C
• Appearance: white or almost white crystalline powder
• Density: 1.033 g/cm³
• Vapor Pressure: 0.00225mmHg at 25°C
• Refractive Index: 1.448
• Storage Temp.: 2-8°C
• PKA: 12.84±0.40(Predicted)
• BRN: 1099836
• CAS DataBase Reference: (S)-(-)-4-TERT-BUTYL-2-OXAZOLIDINONE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(-)-4-TERT-BUTYL-2-OXAZOLIDINONE(54705-42-9)
• EPA Substance Registry System: (S)-(-)-4-TERT-BUTYL-2-OXAZOLIDINONE(54705-42-9)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 54705-42-9(Hazardous Substances Data)

Usage

Chemical Properties

White powder, Crystals, Crystalline powde

Uses

Versatile chiral auxiliary for asymmetric synthesis. For a recent review, see Aldrichimica Acta .

InChI:InChI=1/C7H13NO2/c1-7(2,3)5-4-10-6(9)8-5/h5H,4H2,1-3H3,(H,8,9)/t5-/m1/s1

Downstream Products

• 464171-83-3 4-tert-butyl-2-methoxy-4,5-dihydro-oxazole 
• 478918-64-8 (Z)-4-tert-butyl-3-(2-phenylpropenyl)oxazolidin-2-one 
• 478918-65-9 (E)-4-tert-butyl-3-(2-phenylpropenyl)oxazolidin-2-one 
• 909731-29-9 (4S,1'S,6'S)-3-[(4',6'-dimethylcyclohex-3'-ene-1'-yl)carbonyl]-4-tert-butyloxazolidin-2-one 
• 204851-46-7 (S)-4-tert-butyl-3-(2'-phenylacetyl)oxazolidin-2-one 
• 153729-80-7 (S)-3-benzoyl-4-tert-butyloxazolidin-2-one 
• 878194-06-0 (R)-pentafluorophenyl 2-phenylpropionate 

Relevant articles and documents

METHOD FOR SYNTHESISING OPTICALLY ACTIVE PIPERIDINES BY THE HYDROGENATION OF OPTICALLY ACTIVE PYRIDINES

The invention relates to a method for preparing optically active piperidines by the hydrogenation of pyridines using a suitable catalyst. Said method enables the preparation of a plurality of piperidine derivatives with high optical purity and in high yields.