54752-41-9Relevant academic research and scientific papers
Superfast synthesis, antibacterial and antifungal studies of halo-aryl and heterocyclic tagged 2,3-dihydro-1H-inden-1-one candidates
Shinde, Rahul A.,Adole, Vishnu A.,Jagdale, Bapu S.,Pawar, Thansing B.
, p. 649 - 658 (2021)
We describe a successful synthesis of halo-aryl and heterocyclic labelled 2,3-dihydro-1H-inden-1-one derivatives, as well as their antibacterial and antifungal properties. A total of 15 derivatives from 2,3-dihydro-1H-inden-1-one were synthesized by grind
In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase
Korotchenko, Vasiliy N.,Saydmohammed, Manush,Vollmer, Laura L.,Bakan, Ahmet,Sheetz, Kyle,Debiec, Karl T.,Greene, Kristina A.,Agliori, Christine S.,Bahar, Ivet,Day, Billy W.,Vogt, Andreas,Tsang, Michael
, p. 1436 - 1445 (2014/07/21)
Dual specificity phosphatase 6 (DUSP6) functions as a feedback attenuator of fibroblast growth factor signaling during development. In vitro high throughput chemical screening attempts to discover DUSP6 inhibitors have yielded limited success. However, in
