54757-48-1 Usage
Uses
Used in Pharmaceutical Industry:
Isostemofoline is used as a potential antitumor agent for its ability to inhibit tumor growth and progression. Its anti-inflammatory properties also make it a candidate for the development of treatments for inflammatory conditions.
Used in Neurodegenerative Disease Treatment:
Isostemofoline is used as a potential cholinesterase inhibitor for the treatment of Alzheimer's disease, as it may help improve cognitive function and slow the progression of the disease.
Further research is needed to fully understand the pharmacological and therapeutic potential of isostemofoline and to explore its applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 54757-48-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,7,5 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 54757-48:
(7*5)+(6*4)+(5*7)+(4*5)+(3*7)+(2*4)+(1*8)=151
151 % 10 = 1
So 54757-48-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H22O2/c1-7-16(5,17)9-8-14-11(2)10-15(18-6)13(4)12(14)3/h7-10,17H,1H2,2-6H3/b9-8+
54757-48-1Relevant academic research and scientific papers
PROCESS FOR PREPARATION OF ACITRETIN
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Page/Page column 9, (2016/04/20)
The present invention provides a process for preparation of {(2E,4E,6E,8E)-9-(4-methoxy-2,3,6- trimethyl)phenyl-3,7-dimethyl-nona-2,4,6,8}tetraenoate, an acitretin intermediate of formula (VI) with trans isomer ≥97%, comprising of reacting 3-formyl-crotonic acid butyl ester of formula (V), substantially free of impurities, with 5-(4-methoxy-2,3,6-trimethylphenyl)-3- methyl-penta-2,4-diene-l-triphenyl phosphonium bromide of formula (IV) and isolating resultant compound of formula (VI), treating the filtrate with iodine for isomerization of the undesired cis intermediate and finally obtaining acitretin (I), with desired trans isomer ≥97%.
