54767-81-6

Basic information

• Product Name: 1-(3,4,5-TriMethoxyphenyl)oxirane
• Synonyms: 1-(3,4,5-TriMethoxyphenyl)oxirane
• CAS NO: 54767-81-6
• Molecular Formula: C₁₁H₁₄O₄
• Molecular Weight: 211.2344
• Mol File: 54767-81-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 54-55 °C
• Boiling Point: 127-129 °C(Press: 4-5 Torr)
• Appearance: /
• Density: 1.164±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(3,4,5-TriMethoxyphenyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,4,5-TriMethoxyphenyl)oxirane(54767-81-6)
• EPA Substance Registry System: 1-(3,4,5-TriMethoxyphenyl)oxirane(54767-81-6)

Safety Data

• Hazardous Substances Data: 54767-81-6(Hazardous Substances Data)

Usage

General Description

1-(3,4,5-Trimethoxyphenyl)oxirane, also known as “trimethoxyphenyl oxirane,” is an organic compound with the molecular formula C12H16O4. It is an epoxide, which is a cyclic ether with a three-membered ring. This chemical is commonly used as a reagent in organic synthesis, particularly in the preparation of various biologically active compounds. It is also utilized as a precursor for the synthesis of other complex organic molecules. The compound’s structure includes a phenyl group with three methoxy substituents, which makes it a versatile building block for creating diverse organic compounds with specific properties and functionalities. Additionally, it has been studied for its potential pharmaceutical and medicinal applications due to its interesting chemical reactivity and ability to act as a scaffold for drug development.

Upstream product

• 2181-44-4 trimethylsulfonium methylsulfate 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 134-96-3 syringic aldehyde 
• 51490-01-8 1-(3,4,5-trimethoxyphenyl)-2-bromoethanone 
• 1774-47-6 trimethylsulfoxonium iodide 
• 70775-39-2 dimethylsulfoxonium methylide 
• 75-18-3 dimethylsulfide 
• 77-78-1 dimethyl sulfate 
• 2181-42-2 trimethylsulphonium iodide 
• 6814-64-8 methylenedimethyl sulfurane 

Downstream Products

• 54767-83-8 1-(3,4,5-trimethoxyphenyl)-2-(tert-butylamino)ethanol, hydrochloride 
• 1107692-36-3 (2R)-2-(3,4,5-trimethoxyphenyl)oxirane 
• 177472-80-9 (2S)-2-(3,4,5-trimethoxyphenyl)oxirane 
• 177329-69-0 (S)-1-(3,4,5-trimethoxyphenyl)-1,2-ethanediol 
• 4838-96-4 N-methyl-3,4,5-trimethoxyphenethylamine 
• 1885-35-4 3,4,5-trimethoxybenzonitrile 
• 191671-18-8 2-methoxy-1-(3,4,5-trimethoxyphenyl)-1-ethanone 
• 5320-31-0 3,4,5-trimethoxyphenylacetaldehyde 
• 102104-68-7 3-<6-<2-hydroxy-2-(3,4,5-trimethoxyphenyl)ethylamino>hexyl>-1,3-thiazolidine 

Relevant articles and documents

Simple Syntheses of Marine Alkaloid, (+/-)-Chelonin A, and its Analogs

The first total synthesis of (+/-)-chelonin A and syntheses of its analogs are achieved based on 1-hydroxyindole chemistry.

Solvolysis, Electrochemistry, and Development of Synthetic Building Blocks from Sawdust

Either aldehyde or cinnamyl ether products can be selectively extracted from raw sawdust by controlling the temperature and pressure of a solvolysis reaction. These materials have been used as platform chemicals for the synthesis of 15 different synthetic substrates. The conversion of the initial sawdust-derived materials into electron-rich aryl substrates often requires the use of oxidation and reduction chemistry, and the role electrochemistry can play as a sustainable method for these transformations has been defined.

Synthesis of some electron-rich aryl(hetaryl)oxiranes under phase-transfer and homogeneous conditions

Reactions of mono-, di-, and trimethoxybenzaldehydes with trimethylsulfonium methyl sulfate readily occur under mild homogeneous and heterogeneous phase-transfer conditions to give the corresponding aryloxiranes whose yields are comparable with those typi