547735-00-2Relevant academic research and scientific papers
N2,N2′-disubstituted oxalic acid bishydrazides: Novel ligands for copper-catalyzed Ci￡N coupling reactions in water
Meng, Fei,Wang, Chenxia,Xie, Jianwei,Zhu, Xinhai,Wan, Yiqian
experimental part, p. 341 - 347 (2012/05/04)
A series of N2,N2′-disubstituted oxalic acid bishydrazides were synthesized. Some, for example, N2,N 2′-di-1-(4-methoxyphenyl)-ethanyloxylic-(bishydrazide), are novel and effective ligands for copper-catalyzed Ullmann-type Ci￡N coupling reaction in water. A variety of amines could be effectively N-arylated with aryl halides under both microwave irradiation and conventional heating (even at 30 °C) with good to excellent yields.
