54785-16-9Relevant academic research and scientific papers
A formal new access to the benzo[c]phenanthridine alkaloids, synthesis of Nitidine and O-Methyl Fagaronine analogues
Janin,Bisagni
, p. 10305 - 10316 (2007/10/02)
Previously unreported 2-aryl-1-naphthylamines were obtained in good yields from 2-aryl-1-tetraloneoximes by using the Semmler-Wolf reaction but omitting the acetic anhydride usually present in the reaction mixture. From these amines, through the thermal cyclization of their corresponding ethyl carbamates, a new access to the benzo[c]phenanthridin-6(5H)-ones was found. Preparation of water-soluble Nitidine and O-Methyl Fagaronine analogues bearing an alkylamino side chain on the C-6 position was achieved from these compounds.
Preparation and antileukemic activity of some alkoxybenzo[c]phenanthridinium salts and corresponding dihydro derivatives
Zee Cheng,Cheng
, p. 66 - 71 (2007/10/05)
Salts of 2,3,8,9 tetrasubstituted alkoxy, hydroxy, and acetoxybenzo[c]phenanthridines as well as the corresponding 6 methoxy 5,6 dihydrobenzo[c]phenanthridines were prepared from appropriate chalcones through the tetralone and the 4b,10b,11,12 tetrahydrob
