54818-21-2Relevant academic research and scientific papers
The Formation of 2,3-Disubstituted Thiazolidin-4-ones from S-α'-Aminomercaptoacetic Acid Derivatives
Tierney, John
, p. 997 - 1001 (2007/10/02)
Variously substituted N-benzylidineanilines rapidly react with thioglycolic acid to generate S-α'-aminomercaptoacetic acid derivatives.The latter subsequently cyclize to the corresponding 2,3-diarylthiazolidin-4-ones.Kinetics for the first order cyclization reaction in the solvents toluene, carbon tetrachloride and nitrobenzene have been obtained over the temperature range 333 K to 383 K and are in accord with a neutral, but geometrically complex transition state.
