54826-57-2

Upstream product

• 24892-63-5 1-allyloxy-2-iodobenzene 
• 533-58-4 2-Iodophenol 

Downstream Products

• 136838-43-2 4-[2-((1S,4R)-4-Hydroxy-cyclopent-2-enyloxy)-3-iodo-phenyl]-butyric acid ethyl ester 
• 136838-41-0 4-[2-(tert-Butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-butyric acid ethyl ester 
• 136838-40-9 (E)-4-[2-(tert-Butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-but-2-enoic acid ethyl ester 
• 136838-42-1 4-(2-Hydroxy-3-iodo-phenyl)-butyric acid ethyl ester 
• 136838-39-6 [2-(tert-Butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-acetaldehyde 

Relevant academic research and scientific papers

Synthesis of benzoprostacyclins using palladium catalysis

A method is provided for preparing benzoprostacyclins by the palladium-catalyzed tandem alkene insertion into a 1,4-bisoxy-substituted cyclopent-2-ene intermediate.

Free radical-catalyzed synthesis of benzoprostacyclins

A method is provided for preparing benzoprostacyclins by the free-radical-catalyzed tandem alkene insertion into a 1,4-bisoxy-substituted cyclopent-2-ene intermediate.

Efficient Free-Radical and Palladium-Catalyzed Tandem Alkene Insertions: A New Approach to Benzoprostacyclins

Several stereoisomeric benzoprostacyclins are readily available from a common intermediate (11) via free-radical and palladium-promoted tandem alkene insertion processes.