54832-84-7

Upstream product

• 101750-95-2 (1S,7aS)-(+)-1-acetoxy-5,6,7,7a-tetrahydro-7a-ethyl-4-phenylsulfonylmethyl-indan-5-one 
• 50-00-0 formaldehyd 
• 33878-95-4 (S)-7a-ethyl-2,3,7,7a-tetrahydro-(6H)-indene-1,5-dione 
• 618-41-7 Benzenesulfinic acid 
• 73401-98-6 2-(2-Phenylsulfanyl-ethyl)-[1,3]dithiane 
• 101765-06-4 (2R,3S)-(+)-2-ethyl-2-(3'-oxo-5'-phenylsulfonyl-amyl)-3-acetoxy-cyclopentanone 
• 101750-92-9 (2R,3S)-(+)-2-ethyl-2-(3'-oxo-5'-phenylthio-amyl)-3-acetoxy-cyclopentanone 
• 101750-88-3 2-ethyl-2-(3'-oxo-5'-phenylthio-amyl)-cyclopentane-1,3-dione 
• 101765-05-3 (2R,3S)-(+)-2-ethyl-2-(3'-oxo-5'-phenylthio-amyl)-3-hydroxy-cyclopentanone 
• 108-98-5 thiophenol 
• 101750-87-2 3-oxo-5-phenylthio-amyl mesylate 
• 101750-85-0 2-[2-(2-Phenylsulfanyl-ethyl)-[1,3]dithian-2-yl]-ethanol 
• 101750-86-1 phenyl 3-oxo-5-hydroxy-amyl sulfide 

Downstream Products

• 54832-85-8 (3aS,4S,7aS)-7a-Ethyl-2,3,3a,6,7,7a-hexahydro-4-<(phenylsulfonyl)methyl>-1H-inden-1,5(4H)-dion 
• 54832-85-8 (+)-(7aS)-7a-ethyl-4-(phenylsulphonylmethyl)perhydroindan-1,5-dione 

Relevant academic research and scientific papers

NEW SYNTHESIS OF TWO OPTICALLY ACTIVE STEROID CD RING SYNTHONS BY MICROBIAL ASYMMETRIC REDUCTION

Two optically active steroid CD ring synthons 4 and 19 were synthesized from 11 obtained by the microbial asymmetric reduction of a pro-chiral trione 10 which could be efficiently prepared by the reaction of a new annelating reagent 9 with 2-ethyl-cyclope

Total Synthesis of Dinordrin and Analogues

A total synthesis of optically active dinordrin (3c) is detailed, following a flexible and stereoselective route.A number of unexpected and potentially useful by-products have been identified.The preparation of the novel A-nor-steroid analogues (19), (20)

Process for the preparation of 13β-alkyl-4-gonene-3,17-diones

Novel process for the preparation of 13β-alkyl-4-gonene-3,17-diones of the formula STR1 wherein R1 is methyl or ethyl, consists of REACTING A 7Aβ-ALKYL,5,6,7,7A-TETRAHYDROINDANE-1,5-DIONE WITH FORMALDEHYDE AND AN ARYLSULFINIC ACID OR AN ADDUCT OF FORMALDEHYDE AND ARYLSULFINIC ACID TO PRODUCE A TETRAHYDROINDANE DERIVATIVE; Hydrogenating the tetrahydroindane derivative with hydrogen in the presence of a palladium-, platinum-, or rhodium-containing hydrogenation catalyst to produce a perhydroindane derivative; Condensing the perhydroindane derivative in the presence of a proton-accepting agent with a 7,7-alkylenedioxy-3-oxooctanoic acid ester; Treating the product obtained with a strong aqueous base and then heating the product in an inert solvent to produce a 4,5-secosteroid; Hydrogenating the 4,5-secosteroid in the presence of a palladium-, platinum-, rhodium-, or nickel-containing hydrogenation catalyst; and Hydrolyzing and cyclizing the hydrogenated 4,5-secosteroid by treatment with a strong acid.