54840-34-5

Usage

Uses

Used in Organic Chemistry:
(4-Ethyl-phenyl)-hydrazine is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new and effective compounds for medical and agricultural applications.
Used in Medicinal Chemistry:
(4-Ethyl-phenyl)-hydrazine is used as a reagent in the preparation of other organic compounds, particularly in the synthesis of potential anti-tumor agents. Its study in this field highlights its importance in the development of novel cancer treatments.
Used in Research and Development:
Due to its potential as an anti-tumor agent, (4-Ethyl-phenyl)-hydrazine is utilized in research and development for exploring its properties and applications in the field of medicinal chemistry, with the aim of discovering new therapeutic agents.
Safety Note:
It is crucial to handle (4-Ethyl-phenyl)-hydrazine with caution, as it is classified as a hazardous material due to its toxic and carcinogenic properties. Proper safety measures should be taken during its use to minimize health risks.

InChI:InChI=1/C8H12N2/c1-2-7-3-5-8(10-9)6-4-7/h3-6,10H,2,9H2,1H3

Upstream product

• 589-16-2 4-aminoethylbenzene 

Downstream Products

• 77691-75-9 Acetaldehyde p-ethylphenylhydrazone 
• 85654-56-4 propionaldehyde p-ethylphenylhydrazone 
• 85654-55-3 acetone p-ethylphenylhydrazone 
• 80823-83-2 N-(4-Ethyl-phenyl)-N'-[1-phenyl-1-(5-phenyl-[1,2,4]oxadiazol-3-yl)-meth-(Z)-ylidene]-hydrazine 
• 915306-33-1 1-(4-ethyl-phenyl)-6-(4-iodo-phenyl)-3-trifluoromethyl-1,4,5,6-tetrahydro-pyrazolo[3,4-c]pyridin-7-one 
• 915306-38-6 4'-[1-(4-ethyl-phenyl)-7-oxo-3-trifluoromethyl-1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridin-6-yl]-biphenyl-2-carbaldehyde 
• 863641-46-7 1-(4-ethylphenyl)-3-(2-nitrophenyl)-1H-pyrazole-4-carbaldehyde 
• 863641-57-0 1-(4-ethylphenyl)-3-(2-nitrophenyl)-1H-pyrazole-4-carboxylic acid 
• 863641-68-3 1-(4-ethylphenyl)-3-(2-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester 
• 5599-49-5 3-ethyl-9H-carbazole 

Relevant academic research and scientific papers

Antioxydant activity of β-carboline derivatives in the LDL oxidation model

A series of β-carboline compounds were synthesized, starting from compound GWC22, their antioxidant activity was determined by inhibition of lipid peroxidation. The oxidation of LDL was induced in the presence of CuSO 4 or 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH). The protective actions of these compounds against the cytotoxicity were evaluated with lactate dehydrogenase (LDH) activity in bovine aortic endothelial cells (BAECs) and cellular vitality by measuring mitochondrial activity in the presence of MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide). Most of compounds showed an higher antioxidant activity than GWC22 derivative (R = 1.6 for 5 μM CuSO4). The best antioxidant activities are phenolic and benzyloxy derivatives with ratio R = 1.9 to 2.8 for 1 μM CuSO4. These substances have protective actions and increase significantly the cell viability.

Carbazole methyl malonates

A process for the preparation of α-methyl-carbazole-2-acetic acids, which comprises reacting an α-methyl-3-oxocyclohexane malonic acid di-lower alkyl ester with a substituted phenylhydrazine, and thereafter sequentially oxidizing and hydrolyzing the reaction product to obtain the desired acid, is described.

Heterocyclic compounds

Optionally substituted 4-oxo-1,4-dihydrocinnolin-3-ylpropionic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, and a method of treatment using them. A representative compound is ethyl 6-ethyl-1-methyl-4-oxo-