548458-86-2Relevant academic research and scientific papers
Synthesis of dopamine transporter selective 3-{2-(diarylmethoxyethylidene)}-8-alkylaryl-8-azabicyclo[3.2.1]octanes
Bradley, Amy L.,Izenwasser, Sari,Wade, Dean,Cararas, Shaine,Trudell, Mark L.
, p. 629 - 632 (2003)
A series of 3-{2-(diarylmethoxyethylidene)}-8-alkylaryl-8-azabicyclo[3.2.1]octanes was synthesized and the binding affinities of the compounds were determined at the dopamine and serotonin transporters. The 8-phenylpropyl analogues 8a (Ki=4.1 n
Further structure-activity relationship studies on 8-substituted-3-[2- (diarylmethoxyethylidenyl)]-8-azabicyclo[3.2.1]octane derivatives at monoamine transporters
Cararas, Shaine A.,Izenwasser, Sari,Wade, Dean,Housman, Amy,Verma, Abha,Lomenzo, Stacey A.,Trudell, Mark L.
experimental part, p. 7551 - 7558 (2012/01/03)
The synthesis and structure-activity relationships of 8-substituted-3-[2- (diarylmethoxyethylidenyl)]-8-azabicyclo[3.2.1]octane derivatives were investigated at the dopamine transporter (DAT), the serotonin transporter (SERT) and norepinephrine transporte
