548461-23-0Relevant articles and documents
Diastereoselective synthesis of linear-fused tricyclic nitrogen heterocycles by a tandem reduction-reductive amination reaction
Bunce, Richard A.,Herron, Derrick M.,Lewis, Jason R.,Kotturi, Sharadsrikar V.,Holt, Elizabeth M.
, p. 101 - 106 (2003)
A two-step diastereoselective synthesis of linear-fused tricyclic nitrogen heterocycles has been developed from cyclic β-ketoesters. The cyclization substrates are readily prepared by alkylation of the methyl 2-oxo-cycloalkanecarboxylates with 2-nitrobenz